MALDI mass spectrometry

The new version of the mass spectrometry-based system adds 144 microbial species to its database and includes new tools for sample preparation.

With the exception of Thermo Fisher Scientific, which released three new instruments, vendors focused mainly on expanded applications of existing platforms.

Certain alleles at two SNP sites in TP53 coincided with decreased colorectal cancer risk or an earlier time of disease onset in a study of almost 300 Taiwanese individuals with Lynch syndrome.

Unlike MALDI-based microbial ID efforts from companies like Bruker and BioMérieux, the SimulTOF effort is focused not on clinical work but rather research uses.

Conference attendees discussed the growing number of MALDI-TOF applications while recognizing that LDT regulation poses a particular threat to mass spec-based tests.

NEW YORK (GenomeWeb News) – The National Cancer Institute has awarded Labcyte $1 million to create a process for detecting cancer-associated proteins in samples, the company announced today.

NEW YORK (GenomeWeb News) – Bruker said today that it has entered an agreement with Loos, France-based biotech firm ImaBiotech to distribute that company's Quantinetix software for MALDI mass spec imaging.

NEW YORK (GenomeWeb News) – CovalX and Bruker's Daltonics division today announced an agreement to combine their technologies to support research into protein interactions and macromolecular characterization.

NEW YORK (GenomeWeb News) – Bruker said today it has signed an exclusive patent license agreement with 3M Company that allows it to include in its products patented 3M technology related to MALDI mass spec imaging.

NEW YORK (GenomeWeb News) – Bruker said today it has entered an exclusive partnership with German software firm Scils for informatics tools supporting MALDI mass spec imaging.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.