MALDI

The platform received 510(k) clearance from the US Food and Drug Administration for the expanded identification of mycobacteria, Nocardia, and molds.

Multi-omics, mass spec-based imaging, and cardiovascular biomarkers received extra attention at MSACL US while small molecules continue to drive the field.

Mass spec instrumentation showed solid growth in Q3, with particular strength in academic and government markets.

While LC-MS/MS workflows using triple quadrupoles and, more recently, Q-TOF and Q-Exactive instruments, have typically dominated discussion of mass spec-based protein quantitation, MALDI mass spec has recently emerged as a potential alternative for such applications.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Shimadzu and Sony DADC have extended a collaboration to develop application-specific, individually barcoded, disposable MALDI targets for regulated and non-regulated markets.

Included are a method for analyzing glycoproteins; a method of direct protein identification using MALDI mass spectrometry; and protein biomarkers for cancer sensitivity.

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The technique is based on a MALDI triple-quadrupole platform and exploits the selective multiple-reaction monitoring transition features of the instrument to circumvent problems resulting from interference that can plague existing methods.

Three German labs have accredited the MALDI Biotyper.

A new agreement will expand Biotyper use in Germany and covers two labs in Poland.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.