machine learning Building off ChatGPT Popularity, Generative AI Starts Finding its Place in Genome Informatics Premium Bioinformaticians, researchers, and commercial software developers worldwide are trying to harness the power of generative AI for genomics without compromising scientific integrity. BostonGene, Hokkaido University to Study Biomarkers of Response in HER2-Positive Breast Cancer The collaborators aim to use BostonGene's algorithms and genomics tools to identify HER2-positive breast cancer patients likely to respond to certain therapies. Google DeepMind Machine Learning Method Predicts Pathogenic Effects of Missense Variants After developing a machine-learning method for predicting variant effects, researchers applied it to all possible missense mutations in human protein-coding sequences. Startup Gero to Advance Epigenetic Biomarker Discovery Through Foxo Technologies Partnership Premium As Gero moves its operations from Russia and Singapore to the US, partner Foxo will provide longitudinal DNA methylation data to inform AI and validate recent research. Researchers Find Gene-Specific Machine Learning Advantages for BRCA Pathogenicity Prediction Premium Two separate papers from Korea and Qatar delved into using gene-specific machine-learning models versus disease-specific and genome-wide machine-learning methods for predicting pathogenicity. Aug 11, 2023 Endometrial Cancer Subtypes, Treatment-Related Clues Uncovered in Multiomic Study Aug 4, 2023 Preprint Casts Doubt on Study Underpinning Microbiome-Based Cancer Dx Test From Micronoma Premium Jul 27, 2023 Sherlock Bioscience to Launch Free AI-Based Operating System for CRISPR Dx Development Premium Jun 28, 2023 Microbiome Firm Intus Bio Acquires Bioinformatics Company Pattern Genomics Jun 15, 2023 Illumina, AstraZeneca, Breast Cancer Canada Partner on Screening, Detection Grants Jun 5, 2023 Broad Institute Data Sciences Platform Aims to Provide Infrastructure, Tools for Global Genomics Premium May 24, 2023 Preterm Birth Biology Unraveled With Multiomics, Machine Learning May 12, 2023 Cofactor Quickly Moving Immunotherapy Predictive Test to Market With Data From Intermountain Spinout Premium May 9, 2023 Culmination Bio, Cofactor Genomics Team up on Study to Advance Immunotherapy Response Test Apr 17, 2023 COPD Risk Loci Uncovered With GWAS, Machine Learning-Based Phenotyping Mar 31, 2023 Digital Pathology Offers New Diagnostics Frontier for Leading Cancer Sequencing Firms Premium Mar 30, 2023 Genialis to Develop Biomarker-Based Cancer Diagnostic Models Premium Mar 29, 2023 Cell-Free DNA Sequencing Can Detect Clonal Hematopoiesis in Cancer Patients Mar 29, 2023 Genialis Closes $13M Series A Funding Round Mar 17, 2023 Advanced Cancer Outcomes Predicted Using Model Based on Circulating Tumor DNA Metrics Mar 13, 2023 Ocean Genomics Sees Accenture Ventures Investment as Ticket to Big Pharma Premium Feb 16, 2023 Machine Learning Algorithm Predicts Efficiency of Prime Editing Insertions Feb 16, 2023 M2Gen, Zephyr AI Partner on Cancer Drug Discovery Feb 13, 2023 Sophia Genetics, AstraZeneca Add Multimodal Approach to Cancer Drug Development Partnership Feb 13, 2023 Hexagon Bio Closes $77.3M Series B Financing Round Load More Breaking News SEC Concludes CareDx Investigation, Recommends No Enforcement Action Streck Quality Controls for DiaSorin's Luminex Sepsis Tests Receive FDA Clearance Adela Closes $48M Financing to Develop Cancer Monitoring, Early Detection Test 3EO Health At-Home Molecular COVID-19 Test Nabs FDA EUA Top Five Articles on GenomeWeb Last Week: IVDR Rollout, AI in Genomics, 10x vs. NanoString, More The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.