long fragment read technology

This Week in PNAS

In PNAS this week: functional genomic study of effects of anti-parasitic drugs, humped bladderwort genome assembly, and more.

In Genome Research this week: longitudinal study of Burkholderia cenocepacia isolates from cystic fibrosis patients, long-read assembly approach, and more.

The approach, which uses 10x Genomics technology for haplotyping, requires neither mutation-specific assays nor DNA from affected family members.

Researchers from Pacific Biosciences and elsewhere tested their approach on Arabidopsis thaliana before applying it to wine grape and coral fungus genomes.

The PGP team used Complete Genomics' Long-Fragment Read technology to analyze the set of samples.

More than half the transcripts Cold Spring Harbor Laboratory researchers captured were novel, including novel isoforms of known genes.

The company recently unveiled the newest editions of its Fragment Analyzer platforms and an expanded portfolio of kits, and announced a partnership with Pacific Biosciences.

Both companies are working together to market both companies' technology for long-read DNA sequencing. 

The new genome assembly for a western lowland gorilla named Susie has fewer gaps than a prior assembly produced from short reads and Sanger sequencing.

The PNAS study says foreign genes account for only 1 percent of tardigrade genomes, compared to 17 percent as claimed in a previous study.

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The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.

Oxford researchers are turning to virtual reality to visualize genes and regulatory elements, Phys.org says.

In Science this week: neutrophils rely on microRNA to protect against lung inflammation, and more.

China is moving forward with plans to sequence a million citizens, the Wall Street Journal reports.