linkage analysis COVID-19 Genetic Risk Factor Passed Down From Neanderthals, Study Finds A gene cluster inherited by modern humans from Neanderthals was recently identified as a risk locus for respiratory failure following SARS-CoV-2 infection. PNAS Papers on Coronavirus Pathogenicity, RNA Modification-Related Mutations, PRDD-Seq In PNAS this week: features linked to coronavirus pathogenicity, multi-system syndrome linked to RNA modification-linked mutations, and more. Numerous Variants in Single Gene Linked to Decreased Blood Oxygen During Sleep The researchers combined a linkage analysis followed by whole-genome sequencing data to link the DLC1 gene to blood oxygen levels during sleep. New Mosquito Genome Expected to Serve as Infectious Disease Resource With long-read sequencing, mapping, and other approaches, researchers assembled a high-quality genome for Aedes aegypti, a notorious infectious disease vector. Alzheimer's Disease Study Finds Potentially Protective Genetic Variants Based on the results, RAB10 could be a promising therapeutic target for the prevention of Alzheimer's. Feb 27, 2017 Mutations in DCC Gene Linked to Multiple Brain Malformation Conditions Mar 30, 2016 Familial Autoinflammatory Disease Traced to Missense Mutation in MEFV Feb 4, 2016 Family Study Uncovers Mutation Involved in Rare Vibration Allergy Dec 28, 2015 Harvard, Peking University Team Combines NGS, Linkage Analysis to Detect Aneuploidy, SNVs for PGD Premium Jul 9, 2015 Team Pins Susceptibility to Innocuous Bacteria, Fungi on Mutations in Single Gene Jun 19, 2015 Genomic Analysis IDs New Gene Related to Immunodeficiency May 15, 2014 Linkage Analysis, Exome Sequencing Uncover Novel Variants Associated with Metabolic Syndrome May 28, 2013 Multiple Variants within Signaling Pathway Linked to Schizophrenia Oct 5, 2010 Linkage Analysis Combined with Targeted Sequencing Locates Disease Gene in Microcephaly Premium Breaking News Delic Partners With GT Research for Genetic Analysis of Cannabis, Psychedelic Mushrooms Indivumed, Biognosys Expand Partnership to Offer Immunopeptidomics Insights Multiomic Study Identifies Drivers of Severe COVID-19 in Patients Under 50 Without Comorbidities Yourgene H1 2022 Revenues More Than Double Gencove Raises $10M in Series A Financing Blueprint Genetics, BioMarin to Offer Genetic Testing for Skeletal Dysplasia in Europe, Middle East The Scan Should've Been Spotted Sooner Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier. For Martian Fuel Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo. To Boost Rapid Testing The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests. PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.