linkage analysis COVID-19 Genetic Risk Factor Passed Down From Neanderthals, Study Finds A gene cluster inherited by modern humans from Neanderthals was recently identified as a risk locus for respiratory failure following SARS-CoV-2 infection. Numerous Variants in Single Gene Linked to Decreased Blood Oxygen During Sleep The researchers combined a linkage analysis followed by whole-genome sequencing data to link the DLC1 gene to blood oxygen levels during sleep. New Mosquito Genome Expected to Serve as Infectious Disease Resource With long-read sequencing, mapping, and other approaches, researchers assembled a high-quality genome for Aedes aegypti, a notorious infectious disease vector. Alzheimer's Disease Study Finds Potentially Protective Genetic Variants Based on the results, RAB10 could be a promising therapeutic target for the prevention of Alzheimer's. Computational Model Offers Clues to Missing Heritability for Complex Human Traits Researchers applied a SNP heritability model called LDAK to genetic data for a range of human traits, uncovering relatively high levels of variance explained by SNPs. Feb 27, 2017 Mutations in DCC Gene Linked to Multiple Brain Malformation Conditions Mar 30, 2016 Familial Autoinflammatory Disease Traced to Missense Mutation in MEFV Feb 4, 2016 Family Study Uncovers Mutation Involved in Rare Vibration Allergy Dec 28, 2015 Harvard, Peking University Team Combines NGS, Linkage Analysis to Detect Aneuploidy, SNVs for PGD Premium Jul 9, 2015 Team Pins Susceptibility to Innocuous Bacteria, Fungi on Mutations in Single Gene Jun 19, 2015 Genomic Analysis IDs New Gene Related to Immunodeficiency May 15, 2014 Linkage Analysis, Exome Sequencing Uncover Novel Variants Associated with Metabolic Syndrome May 28, 2013 Multiple Variants within Signaling Pathway Linked to Schizophrenia Oct 5, 2010 Linkage Analysis Combined with Targeted Sequencing Locates Disease Gene in Microcephaly Premium Breaking News Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds Kiromic BioPharma Acquires InSilico Solutions Bio-Rad Laboratories, 10x Genomics Settle IP Lawsuits, Sign Global Cross-Licensing Agreement Scope Fluidics Obtains CE Mark for PCR-Based SARS-CoV-2 Panel MeMed COVID-19 Prognostic Test Receives CE Mark ERS Genomics Licenses CRISPR IP to Japan SLC The Scan Dropped Charges The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal. More Kids The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children. PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more. Purnell Choppin Dies Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.