laser capture microdissection

The method uses hydrogel encapsulation, which mimics a tissue sample, in order to allow circulating tumor cell isolation and extraction through laser dissection.

The Ivy Glioblastoma Atlas includes newly generated anatomical and transcriptional profiles for dozens of tumors, combined with genomic data from TCGA.

Researchers traced clonal populations with shared copy number profiles back to their location in tissue samples, confirming patterns that may have clinical relevance.

A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.

Researchers at Rotterdam's Erasmus University Medical Center have identified an 11-protein signature that appears to distinguish between more and less aggressive forms of triple-negative breast cancer.

Researchers from George Mason University have completed an analysis of samples and data from the National Cancer Institute's Cancer Genome Atlas (TCGA) project that indicates that laser capture microdissection of tumor samples could improve proteomic analyses.

A recent investigation by the National Cancer Institute's Cancer Genome Atlas consortium into the genetic underpinnings of breast tumors also offers a glimpse of the benefits of including proteomic data in such analyses.

Molecular diagnostics firm Theranostics Health plans to commercially launch the first of its TheraLink diagnostic assays by the first quarter of next year, company officials told ProteoMonitor this week.

The researchers are now using the signatures in trials examining the effectiveness of several breast cancer prevention agents and working to develop a prognostic for stratifying precancer patients according to their chances of progressing to cancer.

Petricoin said the database could help physicians make better treatment decisions, aid pharmaceutical firms' drug-development efforts, and uncover new indications for existing therapies.

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.