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laser capture microdissection

In Genome Research this week: transcriptome assembly algorithm, gene expression among somatic motor neurons in spinal muscular atrophy models, and more.

The sequencing-based analysis also found that some of these cancer-linked alterations in endometrial glands may occur early in life.

The analysis of a hippocampus cell layer uncovered genetic loci associated with schizophrenia risk, including two that may represent drug targets.

The method uses hydrogel encapsulation, which mimics a tissue sample, in order to allow circulating tumor cell isolation and extraction through laser dissection.

The Ivy Glioblastoma Atlas includes newly generated anatomical and transcriptional profiles for dozens of tumors, combined with genomic data from TCGA.

Researchers traced clonal populations with shared copy number profiles back to their location in tissue samples, confirming patterns that may have clinical relevance.

A method called genome architecture mapping, or GAM, brings together deep DNA sequencing and laser microdissected slices of individuals cells in a tissue sample.

Researchers at Rotterdam's Erasmus University Medical Center have identified an 11-protein signature that appears to distinguish between more and less aggressive forms of triple-negative breast cancer.

Researchers from George Mason University have completed an analysis of samples and data from the National Cancer Institute's Cancer Genome Atlas (TCGA) project that indicates that laser capture microdissection of tumor samples could improve proteomic analyses.

A recent investigation by the National Cancer Institute's Cancer Genome Atlas consortium into the genetic underpinnings of breast tumors also offers a glimpse of the benefits of including proteomic data in such analyses.

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President Donald Trump might not approve the stricter standards the US Food and Drug Administration is developing for authorizing a SARS-CoV-2 vaccine, according to Politico.

Wired reports that Oxitec has now developed a genetically modified fall armyworm.

A large genetic study finds SARS-CoV-2 viruses with a certain variant are spreading more than others, according to the Washington Post.

In Nature this week: sister-chromatid-sensitive chromosome conformation capture approach, and more.