laser capture microdissection
Working within I-SPY 2, the researchers identified a signature for determining whether patients are better candidates for anti-HER2 or immune checkpoint therapies.
Max Planck Team Uses Spatial Single-Cell Proteomics Method to Analyze Hepatocyte Heterogeneity
Using a workflow combining laser microdissection and single-cell mass spectrometry, the researchers identified more than 1,700 proteins per liver cell.
Human Brain Circular RNAs Linked to Neuron Type, Neuropsychiatric Conditions
Using deep RNA sequencing, researchers identified cell type- and disease-related circRNAs in brain samples from individuals with or without Parkinson’s or Alzheimer’s disease.
Max Planck Team Develops Workflow Combining Single-Cell Imaging With Deep Proteomic Profiling
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Called deep visual proteomics, the approach allows for the characterization of thousands of proteins in small numbers of cells while retaining spatial information.
Normal Endometrial Glands Harbor Cancer-Associated Mutations, Study Finds
The sequencing-based analysis also found that some of these cancer-linked alterations in endometrial glands may occur early in life.