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isothermal amplification

The company said that it has achieved encouraging results in a preclinical study of the assay, and that if clinical trial results are equally positive it will submit the test for US Food and Drug Administration approval by the end of the summer.

As part of ongoing research to create an "equipment-free" nucleic acid assay, PATH researchers showed in a recent study that electricity-free exothermic reactions can successfully incubate an isothermal nucleic acid assay with results equivalent to commercially available PCR instruments.

The company has developed a cartridge-based, multiplex, sample-to-answer molecular testing platform in the same vein as Cepheid, and hopes to begin clinical trials for its first two tests for detecting Staphylococcus aureus in blood culture and Clostridium difficile in stool by early summer.

Qiagen will supply ESE-Quant Tube Scanners to national health authorities in 35 emerging countries in Africa, Asia, and South America under the Joint FAO/IAEA Programme in veterinary diseases.

ZyGem's acquisition of MicroLab Diagnostics, announced this week, is expected to accelerate the company's transformation from a provider of DNA extraction products to a purveyor of fully integrated DNA-testing platforms for the forensics, biodefense, and eventually clinical diagnostics markets.

Life Tech officials said that Stokes Bio's microfluidics-based technology platform will enable high-throughput, PCR-based genetic analyses for a variety of applications, particularly in the area of agricultural biology.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.