immune repertoire sequencing Immune Signatures Outperform TILs for HER2-Positive Breast Cancer Prognoses Immune-related gene expression signatures tracked more closely with treatment response and outcomes than tumor-infiltrating lymphocytes in early-stage HER2-positive breast cancer. T Cell Receptor Repertoire Analysis Points to Potential Tuberculosis Vaccine Targets Based on sequencing data, researchers cataloged T-cell receptors and identified the epitopes they target in people exposed to Mycobacterium tuberculosis. Adaptive Bio Narrows 2022 Revenue Guidance, Outlines Financial Expectations Releasing Q3 results, the Seattle-based immune system biotechnologies firm set its new full-year revenue guidance to the range of $185 million to $190 million. Adaptive Biotechnologies Halts T-Detect Commercialization, Reports 13 Percent Q2 Revenue Growth Premium The company realized it is costly to develop single-disease T-Detect assays and is deferring commercialization until a clear path to reimbursement is proven. Adaptive Biotech's ClonoSeq Gets Expanded Medicare Coverage For B-Cell Lymphoma The firm's assay is the first and only test to gain coverage for this patient population, for whom ctDNA MRD assessment can help personalize treatment. May 5, 2022 Adaptive Biotechnologies Making Inroads in MRD, Immune Medicine Businesses Premium May 4, 2022 Adaptive Biotechnologies Q1 Revenues Rise Slightly in Q1 Apr 26, 2022 Evaxion Biotech Adopts Personalis Immune Profiling Platform for Melanoma Immunotherapy Trial Mar 3, 2022 Adaptive Biotechnologies Makes Progress Toward T-Cell Assay for Inflammatory Bowel Disease Premium Feb 16, 2022 Adaptive Biotechnologies to Focus on Immune Medicine, Minimal Residual Disease Testing Businesses Premium Feb 15, 2022 Adaptive Biotechnologies Revenues Rise 26 Percent in Q4, 57 Percent in 2021 Dec 17, 2021 A*STAR Wins $2M Chan Zuckerberg Initiative Grant to Advance Asian Immune Cell Atlas Nov 16, 2021 Cancer Genomic Analysis Reveals Distinct Features in Tumors From Patients Under 50 Years Old Nov 3, 2021 Adaptive Biotechnologies Q3 Revenues Rise 50 Percent Aug 4, 2021 Adaptive Biotechnologies Q2 Revenues Jump 83 Percent Jul 9, 2021 Integrated Tumor, Microbiome Features Influence Immunotherapy Combo Effects in Advanced Melanoma Jun 22, 2021 China's Singleron Biotechnologies Pushes Single-Cell RNA-seq Into Clinical, Translational Studies Premium May 6, 2021 Adaptive Biotech Touts Progress Toward Lyme and Gastrointestinal Disease Diagnostics Premium May 5, 2021 Adaptive Biotechnologies Q1 Revenues up 84 Percent, Beat Analyst Estimates Mar 30, 2021 Enpicom, Viroclinics-DDL Expand Partnership to Accelerate Antibody, Vaccine Discovery Feb 25, 2021 Personalis Q4 Revenues up 11 Percent Feb 25, 2021 Adaptive Biotechnologies Touts New Era of T Cell-Based Dx With T-Detect COVID Launch Premium Feb 25, 2021 10x Genomics Acquires Denmark's Tetramer Shop Feb 24, 2021 Adaptive Biotechnologies Q4 Revenues Rise 25 Percent Feb 23, 2021 Adaptive Biotechnologies, LabCorp Expand Collaboration Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.