IHC Akoya Biosciences, AstraZeneca Collaborate on Spatial Biomarker Profiling for Immuno-Oncology The firms will study drug mechanisms of action, confirm the prevalence of targets, and discover predictive signatures for subsequent trial designs. Researchers ID Four Small Cell Lung Cancer Subtypes, Suggest Future Treatment Implications Premium The transcription-based subtypes could differentiate which SCLC patients respond to treatments, such as immune checkpoint inhibitors and PARP inhibitors. Diaceutics, Alva10 Gathering Evidence Base for Improving PD-L1 Test Reimbursement Premium The companies will work with labs to improve payors' understanding of the costs of performing PD-L1 testing and the value it provides to patient care. Indivumed, Ultivue Sign Deal to Integrate Cancer Tissue Analysis Technologies The deal joins Indivumed's collection of tissue biospecimens and immunohistochemistry expertise with Ultivue's multiplex immunofluorescence platform. FDA Approves Merck's Keytruda, Agilent CDx in PD-L1-High Triple-Negative Breast Cancer The agency approved Agilent/Dako's PD-L1 IHC test for identifying TNBC patients who are most likely to respond to Keytruda and chemo. Sep 20, 2020 HPV, p16 May Offer Different Prognostic Clues in Oropharyngeal Cancer, ESMO Data Reveals Premium Jul 22, 2020 Ultivue, OracleBio Collaborate on Tissue Biomarker Analysis Workflow May 29, 2020 Tumor Microbiome Appears to Vary With Cancer Type Feb 25, 2020 10x Genomics Unveils 2020 New Product Pipeline at AGBT Premium Feb 19, 2020 10x Genomics Previews New Product Lineup Ahead of AGBT Premium Nov 5, 2019 Discovery Life Sciences Acquires QualTek Molecular Laboratories Oct 31, 2019 HER2 Amplification Confers Drug Sensitivity Across Tumor Types in New Study Premium Sep 30, 2019 Tempus Finds Tumor-Normal Sequencing, RNA Profiling Aid Patient Matching to Therapies, Trials Aug 8, 2019 Researchers Propose Role For Microbes in Pancreatic Cancer Immune Features, Survival May 10, 2019 NanoString Aims to Drive Interest in Spatial Profiling Platform as Reports Roll in From Early Users Premium Apr 22, 2019 Researchers Seek Best Approach to Identify Lung Cancer Patients With MET-Based Resistance Premium Apr 17, 2019 Non-Small Cell Lung Cancer Mutations, Tumor Microenvironment Profiled in China Mar 4, 2019 Colon Cancer Patients Could Benefit From HER2 EGFR Non-Response Findings, Investigators Say Premium Oct 11, 2018 Researchers Explore Variety of Response Markers in Melanoma Study of Combo Checkpoint Inhibitors Premium Jul 27, 2018 HPV, Polyomavirus Infections Likely Minor Bladder Cancer Contributors, Study Suggests Jul 3, 2018 Georgetown Researchers Develop IHC Assay to Predict Bladder Cancer Recurrence, Spread Premium Jun 21, 2018 Systems Biology Study of Alzheimer's Disease Supports Ties to Virus Jun 4, 2018 MSI Tumor Analysis Implicates Lynch Syndrome in Several New Cancer Types Apr 18, 2018 OncoDNA Study Highlights Use of Multiple Molecular Tests to Improve Cancer Treatment Premium Jan 24, 2018 Lung Cancer Molecular Testing Guidelines Updated by CAP, AMP, IASLC Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.