Researchers used the approach to develop an assay to detect above-threshold triplet repeats in Huntington's disease, but also highlight a variety of other applications.
The British molecular genetics company recently announced a menu update for its SureSeq myPanel NGS Custom Cancer Panel offering.
The firm envisions applying its new PlexSet technology to the upper end of multiplex gene expression analysis as well as CRISPR validation applications.
The new study in NEJM describes six families that share a disorder caused by mutations in IKAROS, a protein that plays a role in immune cell development.
Fred Hutch researchers report that analysis of one metastatic prostate tumor sample captures most of the variation in an individual's various metastases.
In early experiments, the method's raw single pass error rate was approximately 2 percent for a single target and up to 4 percent for a mixture of 10 targets.
The chemistry will be single-molecule, based on hybridization, and will not require amplification, enzymes, or library prep, the firm said.
Reveal will use Affy's ViewRNA in situ hybridization products in combination with its image-analysis software for tissue staining, imaging, and quantification.
The authors have plans to turn the technology into a kit for sequencing panels to be developed by their startup firm, Searna.
The company will focus on gaining customers for its custom and pre-defined hybrid capture kits first in Southern California, and then across the US.
The ancestors of the Arizona bark scorpion and other scorpions and spiders underwent whole-genome duplication, KJZZ reports.
A cryptographic approach could help researchers keep genomic data private while researchers analyze it, Scientific American reports.
Andy Page, the former president of 23andMe, has joined a diabetes-management startup, according to CNBC.
In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.