high-throughput screening BioSpyder Wins High-Throughput Toxicology Screening Contract From EPA The Carlsbad, California-based company said that the contract — its third with the EPA — has a potential value of $25 million over five years. 10x Genomics, Collaborators Develop Targeted Single-Cell Gene Expression Methods Premium These hybrid capture-based methods target gene transcripts of interest, which could shrink sequencing costs for some experiments by as much as 90 percent. Iceland SARS-CoV-2 Screening Effort Finds Lower Infection Incidence in Children, Women The team also found that the proportion of infected people didn't change substantially during the screening period, consistent with beneficial containment. CRISPR Screening Approach for Mapping Genetic Interactions Uncovers Masked Phenotypes The screen, which multiplexes Cas9 and Cas12a, could be used for functional analysis of large genomic regions in mammalian cells, the researchers said. NYGC Researchers Develop CRISPR-Based Screen to Target RNA Viruses Like SARS-CoV-2 Premium The screening platform, which uses the Cas13 nuclease to target RNA instead of DNA, can be used to design guide RNAs for CRISPR research. Jan 15, 2020 Single Technologies Raises $1.6M to Develop NGS Platform Dec 20, 2019 Large Pan-Cancer CRISPR Screens by Broad, Sanger Institutes Show High Concordance Dec 5, 2019 High-Throughput Single-Cell Transcriptomics Assay Facilitates Compound Screens Premium Aug 15, 2019 NIH, UCSF Researchers Develop CRISPRi Platform for Genetic Screening of Human Neurons Apr 10, 2019 Genome-Scale CRISPR Screening Helps Identify New Cancer Drug Targets Mar 28, 2019 Schizophrenia Genes Prioritized in Zebrafish Mutant Study Oct 18, 2018 Mount Sinai Researchers Develop Protein Barcoding Technology for Single-Cell CRISPR Screening May 11, 2018 PARP Inhibitor Resistance Gene Identified Using CRISPR Screen May 3, 2018 Human Malaria Parasite Mutagenesis Highlights Essential Genes, Potential Drug Targets Sep 27, 2017 CRISPR-Cas9 Screen Points to Potential Vulnerabilities in KRAS-Mutated Colorectal Cancer Jul 26, 2017 PLATE-Seq Method Adds Expression, Regulatory Insights to Cell Screens Premium Mar 21, 2017 Bay Area's Innovative Genomics Institute Launches Entrepreneurially Focused 'Super-Postdoc' Program Premium Mar 20, 2017 CRISPR Method Used to Detect Synthetic Lethalities in Cancer Mar 8, 2017 New CRISPR Dual-Guide RNA Library Design Tool Powers Functional Studies of lncRNAs Premium Dec 16, 2016 CRISPR Screen IDs Hundreds of Functional lncRNAs in Human Cells Premium Oct 31, 2016 CRISPR Deletion-Based Screen Identifies Functional Long Non-Coding RNAs Oct 28, 2016 CRISPR Plus Single-Cell Sequencing Combines Benefits of Pooled, Arrayed Screens Feb 18, 2016 Agilent Launches Early-Access Program to Evaluate CRISPR/Cas9 Pooled Guide RNA Libraries Premium Nov 17, 2014 Horizon CombinatoRx to Profile Oncology Asset for Pharma Firm Jul 25, 2014 Horizon CombinatoRx Contracts with Otsuka for Screening of Drug Candidates Load More Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.