high-throughput screening

The program will provide two young scientists with funding for independent research as well as resources to help them commercialize their technology.

The gene-gene interactions research could lead to new therapies targeting cells with particular mutations, or combinations of targeted therapies.

A new user-friendly software tool is helping Rory Johnson of the University of Bern to do genome-wide screening of lncRNA function by deleting promoters.

Researchers at UCSF used CRISPR interference to knockdown lncRNA transcripts, then assayed for cell growth to get the final list of almost 500.

Using two guide RNAs to excise chunks of the genome, an international team identified lncRNAs essential and inhibitory to human cancer cell line proliferation.

A team of Austrian scientists used their new screening method to investigate genes and transcription factors regulating T cell receptor signaling.

The new SureGuide product is based on the same DNA synthesis platform behind the firm's other genomic technologies.

Horizon CombinatoRx will be paid $750,000 for the five-month project. 

NEW YORK (GenomeWeb) – Horizon Discovery today announced that its CombinatoRx division has entered into a contract with Otsuka Pharmaceutical Development and Commercialization to perform in vitro cell line screening of certain OPDC candidates in development.

NEW YORK (GenomeWeb) – The National Institutes of Health plans to fund scientists who will collaborate with established high-throughput screening facilities to discover and develop novel small molecule chemical probes.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.