Both a genome-wide association study and a rare variant burden analysis homed in on a role for KIF5A mutations in amyotrophic lateral sclerosis.
Investigators narrowed in on genes involved in placentation and appetite during a GWAS focused on a severe form of nausea and vomiting in pregnancy.
The researchers also found that genes located near these loci were differentially expressed in healthy versus diseased cartilage.
In Nature this week: method that uses DNA methylation signatures to classify central nervous system tumors, and more.
The researchers uncovered more than 20 new stroke-associated genetic loci, some of which are the targets of antithrombotic drugs.
The researchers conducted a genome-wide association study and other analyses using about 47,000 research participants from 23andMe.
Analyzing samples from Iceland and elsewhere, researchers uncovered one known and two new risk loci for aortic valve stenosis that are also associated with other heart risk pathways.
Using data for nearly 59,000 UK Biobank participants, researchers identified genes and pathways involved in heart rate variability, exercise response, and exercise recovery.
CNN reports that researchers have tied a new variant to opioid addiction risk.
A genome-wide association study that linked common genetic variants to salivary gland carcinoma risk has been retracted, according to Retraction Watch.
An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.
The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.
Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.
In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.