A large meta-analysis and functional genomic assessment of a risky HLA haplotype uncovered hypomethylation that alters immune-related expression at the locus.
An association study involving more than 100,000 individuals led to overlapping and distinct variants involved in bipolar disorder, schizophrenia, and subtypes of each.
Using data for more than 140,000 individuals, researchers narrowed in on 63 new prostate cancer-associated loci and established a polygenic score linked to enhanced risk.
Using genotype and blood plasma protein information for thousands of healthy individuals, researchers documented variants influencing plasma protein levels.
During a webcast to discuss the recent funding announcement for genome centers, project organizers offered details on data generation and return of results.
At least half a dozen cancer phenotypes showed significant associations with GWAS variant-based polygenic risk scores in a new phenome-wide association study.
Using genome sequences for hundreds of ancient individuals, researchers have analyzed population dynamics and displacements around the Eurasian steppe.
Along with a polygenic risk score enhanced in migraine sufferers, new research reveals a high-frequency variant implicated in cold adaptation and migraine in Europeans.
With genome sequences and/or array-based genotypes for ancient and modern individuals in Patagonia, researchers retraced hunter-gatherer population history.
Bloomberg reports that Brainstorm Cell Therapeutics plans to offer a treatment it is developing under the "right to try" law for hundreds of thousands of dollars.
