Results from some 4,200 GWAS suggest a significant subset of genetic loci contribute to multiple complex traits, though the type of overlap further varied at the gene and SNP levels.
In European American military veterans, the study led to several genetic loci with ties to the severity of a core PTSD symptom known as reexperiencing.
A large genome-wide association meta-analysis and follow-up analyses revealed eight risk loci involving SNPs previously associated with body traits, metabolism, and psychiatric risk.
Using samples from heart failure patients and healthy controls, researchers uncovered a gene that, when absent in mice, reduced their risk of heart failure.
Findings from a genome-wide association study suggest that fetal SNPs in SLIT2 and other genes may coincide with the risk of spontaneous preterm birth.
A few key loci appear to contribute to a lasting immune response following childhood immunizations against meningococcal bacteria, tetanus, or Haemophilus influenzae type B.
Using exome data from Alzheimer's disease cases and controls with or without the APOE4 risk allele, investigators identified potential risk-stratifying variants.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
