genotyping arrays
Sepsis Study Untangles Genetic Variants, Regulatory Features Behind High-Risk Subgroup
With genotyping and gene expression data for adult sepsis patients enrolled over more than a decade, researchers explored genetic variation and regulation behind the condition.
Breast Cancer Contributors Uncovered in African Ancestry-Focused Analyses
Newly identified breast cancer risk loci, including subtype-related risk sites, led to an improved breast cancer polygenic risk score in African ancestry individuals.
Telomere Length in White Blood Cells Linked to Malaria Parasite Exposure in Sub-Saharan Africa
Genetic and environmental factors contributed to leukocyte telomere length, which was shorter in regions with the malaria-causing Plasmodium falciparum.
Gut Microbiome Structural Diversity Linked to Genetic Factors in Human Hosts
The researchers found that host genetics, particularly genotypes influencing GalNAc production, could influence which strain of Faecalibacterium grows in the gut.
Reproduction, Lifespan Show Antagonistic Pleiotropy in Genetic Analysis
Using UK Biobank data, researchers found that genetic variants linked to increased reproductive capabilities coincided with shorter lifespan in individuals of European ancestry.