genotyping
Major Depression Contributors Uncovered in Multi-Ancestry GWAS Meta-Analysis
Researchers identified almost 700 major depression-associated variants using genotyping profiles for around 5 million diverse participants with or without major depression.
Problem Drinking Contributors Unearthed Using Mendelian Randomization Study
Researchers narrowed in on cortical proteins and brain cell type-related genes with apparent ties to alcohol use disorders using GWAS and post-mortem multiomic profiling.
Childhood Hearing Loss Symptoms, Severity Informed by Adult Polygenic Risk Score
Using data from two Australian cohorts, researchers found that a PRS for hearing loss in adults could offer clues to childhood hearing loss risk and severity.
Alzheimer's Disease Risk Linked to New Loci in X Chromosome-Wide Association Study
Researchers found Alzheimer's disease risk loci on the X chromosome and focused in on a gene suspected to affect amyloid beta accumulation.
Kidney Cancer Immunotherapy Response Linked to Signature Reflecting HLA, Tumor Immune Activity
Researchers found an immune checkpoint blockade response signature in renal cell carcinoma that reflects tumor immune activity influenced by human leukocyte antigen features.