TreeWAS provides a method for identifying gene variant-phenome associations in heterogenous biobank data without compromising phenotypic resolution.
The release has been accompanied by acute interest from the genomics community, which views the resource as a "game changer" for anyone working in human genetics.
Researchers applied a SNP heritability model called LDAK to genetic data for a range of human traits, uncovering relatively high levels of variance explained by SNPs.
Objectives for this year include building a network of ELIXIR beacons, developing new features and security measures, and partnering with data owners.
The company plans to recruit one million patients from Mexico over three years and then expand to Columbia, Argentina, and Brazil.
The portal offers access to genotype, phenotype, and clinical data related to type 2 diabetes as well as computational tools for querying the information.
The research team linked a mutation in a protein-coding gene to inherited multiple sclerosis and genetic risk factors for developing the disease.
The team found more than a dozen microbe and gene associations that indicate heritability of certain traits in the gut microbiome.
EMBL-EBI's Oliver Stegle is taking a statistical approach to understanding genotype-phenotype associations.
The group has developed tables that match genotype, phenotype, and clinical recommendations to help inform therapy choices at the point of care.
The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.
Oxford researchers are turning to virtual reality to visualize genes and regulatory elements, Phys.org says.
In Science this week: neutrophils rely on microRNA to protect against lung inflammation, and more.
China is moving forward with plans to sequence a million citizens, the Wall Street Journal reports.