Three long-read assemblies — two from PacBio data alone and one from Oxford Nanopore and Illumina data — had considerably more indel errors in genes than short-read assemblies.
OmniTier claims that CompStor performs comparably to standard alignment-based methods but may be a more affordable solution for customers with limited budgets.
Researchers used long-read sequencing to generate more complete chimpanzee and orangutan genome assemblies, which they compared to gorilla and human assemblies.
With FALCON-Phase, investigators used PacBio long reads and Hi-C data from Phase Genomics to assemble a haplotype-phased, diploid genome for a hybrid bull.
