genome assembly
Human Pangenome Reference Consortium Develops 'Semi-Automated' Diploid Genome Assembly Method
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An assembly approach using the graph-based hifiasm algorithm with PacBio HiFi long reads from a sequenced trio was the "clear winner," senior author Erich Jarvis said.
The draft, presented by the Human Pangenome Reference Consortium, includes novel alleles and is the first step on the way to a diverse reference genome.
With Oxford Nanopore Technologies' new R10.4 flow cell and chemistry, researchers generated near-finished microbial genomes using only nanopore long-read sequencing.
T2T Consortium Publishes Early Findings From Complete Human Genome Assembly
In a series of studies, investigators outlined methods used to produce a telomere-to-telomere version of the human genome, while touching on applications of the assembly.
At ABRF Meeting, T2T Consortium Describes Improvements of Complete Human Genome
The new human genome assembly could lead to better variant calling and inform cell biology studies, a consortium of researchers said at the ABRF annual meeting.