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Aug 16, 2019

New Long Read Assemblers for De Novo Genomes Promise Speed, Scalability

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Two BioRxiv preprints describe new algorithms that the developers say can accelerate the pace of genome analysis.

Aug 15, 2019

Nature Describes a Circular Consensus Sequencing Method, CRISPR Platform, More

In Nature this week: circular consensus sequencing method to sequence and assemble a human genome, a new CRISPR platform using the Cpf1 endonuclease, and more.

Aug 01, 2019

Nature Presents Variants Linked to Post-Traumatic Stress Disorder, More

In Nature this week: eight loci linked to PTSD in US Million Veteran Program study, new hybrid metagenomic assembler, and more.

Jun 14, 2019

Almond Genome Points to Regions Affecting Sweet Taste

The researchers sequenced and analyzed the domesticated almond genome, uncovering why they are sweet, unlike bitter wild almonds.

May 30, 2019

Long-Read Metagenomic Sequencing Gets Boost From New Assembly Tool

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Two research groups have released new long-read datasets and a metagenomics-specific genome assembler for the analysis of microbial communities.

May 21, 2019

New Graph-Based Assemblers Promise Speedier, Cheaper Computing for Long-Read Sequencing

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Flye and wtdbg2, both released this year, work with Pacific Biosciences and Oxford Nanopore data and can assemble bacterial and more complex genomes.

Mar 26, 2019

New Human Genome Reference Projects Combine Long Nanopore Reads, Other Data Types

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The Telomere-to-Telomere consortium has already generated a gapless assembly of the human X chromosome and aims to complete all chromosomes over the next two years or so.

Feb 28, 2019

This Week in Nature: Feb 28, 2019

In Nature this week: strawberry reference genome, Antarctic blackfin icefish genome assembly and linkage map, and more.

Feb 26, 2019

This Week in PNAS: Feb 26, 2019

In PNAS this week: early-onset preeclampsia model, lateral gene transfer events in grasses, and more.

Jan 30, 2019

This Week in Genome Research: Jan 30, 2019

In Genome Research this week: collection of circular RNAs from breast cancers, chromosome-scale genome assembly for the axolotl, and more.

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The Scan

To Explain What They Mean

The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.

A Few Days

The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.

Slightly Larger Pool

New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.

Cell Studies Explore Microbiome Genes, Tumor Influence, More

In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.

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  1. New Long Read Assemblers for De Novo Genomes Promise Speed, Scalability

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