genome assembly Human Pangenome Reference Consortium Develops 'Semi-Automated' Diploid Genome Assembly Method Premium An assembly approach using the graph-based hifiasm algorithm with PacBio HiFi long reads from a sequenced trio was the "clear winner," senior author Erich Jarvis said. Draft Human Pangenome Reference Shows the Way to Capturing More Human Diversity Premium The draft, presented by the Human Pangenome Reference Consortium, includes novel alleles and is the first step on the way to a diverse reference genome. New Nanopore Sequencing Chemistry Enables Assembly of Near-Finished Bacterial Genomes Premium With Oxford Nanopore Technologies' new R10.4 flow cell and chemistry, researchers generated near-finished microbial genomes using only nanopore long-read sequencing. T2T Consortium Publishes Early Findings From Complete Human Genome Assembly In a series of studies, investigators outlined methods used to produce a telomere-to-telomere version of the human genome, while touching on applications of the assembly. At ABRF Meeting, T2T Consortium Describes Improvements of Complete Human Genome The new human genome assembly could lead to better variant calling and inform cell biology studies, a consortium of researchers said at the ABRF annual meeting. Jan 3, 2022 Tech-Boosted Genome Assembly Helps Resolve Closely Related Microbes in Metagenomic Sample Oct 20, 2021 Telomere-To-Telomere Consortium Shares Insights From Gapless Human Genome at ASHG Premium Sep 14, 2021 Speedy Long-Read Genome Assembly Enabled by Minimizer-Space Analysis Aug 10, 2021 Cultivated Cotton Genomes Reveal Crop Trait-Related Structural Variants Jul 9, 2021 Human Reference Genome Choice Impacts Variant Calling, but Switching Is Tricky Premium Jun 3, 2021 Telomere-To-Telomere Team Assembles Complete Human Genome En Route to Reference Pangenome Premium May 14, 2021 New California Condor Genome Assembly Reveals High Genetic Diversity Apr 28, 2021 Vertebrate Genomes Project Presents High-Quality Genomes for 25 Species Apr 8, 2021 Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Mar 25, 2021 Wild Animal Gut Microbiomes Reveal New Species, Ties to Host Traits Mar 17, 2021 Giraffe Genome Assembly, Functional Analyses Highlight Variants Linked to Height Adaptations Mar 3, 2021 Human Pangenome Reference Consortium Releases Data From 30 Genomes Feb 19, 2021 NRGene Looks to Royalty-Based Partnerships in Wake of IPO Premium Dec 17, 2020 New Rhesus Macaque Reference Genome Holds Potential for Human Disease, Evolution Research Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 18, 2020 Lurie Children's Hospital Details Migration of Clinical Diagnostics Lab to hg38 Reference Genome Premium Jul 14, 2020 Telomere-to-Telomere Team Shares Complete X Chromosome Assembly Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium May 14, 2020 Pangolin Coronavirus Study Finds No Evidence of Direct Evolution to SARS-CoV-2 Oct 23, 2019 DNAStar Names Inqaba Biotec as Distributor for Africa Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.