Gene Editing & Gene Silencing | GenomeWeb

Gene Silencing/Gene Editing

Researchers are making mutations in a cell's genome to mark it and later read out that information to create cell lineage maps and chemical interaction histories.

Scientists led by Eric Kmiec showed that their strategy of point mutation editing with single-stranded DNA oligos and double-strand breaks works with CRISPR/Cas9. 

The ag-bio giant has landed a worldwide, non-exclusive licensing deal for agricultural applications of the genome-editing technology.

Horizon Discovery, Desktop Genetics, and Vectalys will work together to create fully-licensed, customizable kits for CRISPR/Cas9-based genetic screening.

Cell line engineers from Horizon Genomics said a method to make or undo fusion oncogenes in cell lines could help create reference standards for cancer diagnostics.

Methods and products for expressing proteins in cells
Compositions and methods for gene silencing
Installation of genomes or partial genomes into cells or cell-like systems
Methods and compositions for gene inactivation
Protein having nuclease activity, fusion protein and uses thereof
Construction of new variants of dextransucrase DSR-S by genetic engineering

In PNAS this week: mutations linked to nasopharyngeal carcinoma, salivary proteins common among oral squamous cell carcinoma patients, and more.

At Wired, a science journalist discusses her decision not to undergo BRCA testing.

The Japan Times says regulations are needed to oversee human genome-editing research.

In PLOS this week: molecular surveillance of S. Typhi, genome-wide association study of attention in children, and more.