Gene Silencing/Gene Editing

The bodies will assemble an international committee to guide future research and have planned a summit this fall for experts to discuss the implications of the technology.

Commercial software packages with a suite of additional features offer an alternative to academic guide RNA design tools for CRISPR/Cas9 genome editing.

High-throughput, systematic screens found 25 protein domains essential to AML, including six that are already drug targets in clinical trials.

The North Carolina-based firm plans to use the money to continue development of its Arcus genome editing platform.

The scientists will try to develop a platform that can find and edit genes responsible for key traits such as plant yield and disease resistance.

Engineering and optimization of systems, methods, and compositions for sequence manipulation with functional domains
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
Method for expression of small RNA molecules within a cell
Analyzing messenger RNA and microRNA in the same reaction mixture
Methods and compositions for detection of small RNAs
Identification of microRNAs (miRNAs) in fecal samples as biomarkers for gastroenterological cancers

In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.