Gene Silencing/Gene Editing

The Cas9 enzyme from S. aureus can be delivered by a viral vector and could lead to more CRISPR-based research tools and novel study designs in animal models.

Hairpin will be the exclusive agent for negotiating and executing new license agreements for patents covering the CSHL RNAi technology.

The findings build on previous work that showed a gene known to be regulated by an miRNA family influenced the growth of fruit in Arabidopsis.

Inhibiting the non-homologous end-joining DNA repair mechanism led to an eightfold increase in efficiency of gene knock-ins.

The investment from the UK will create an integrated biology research complex with lab space for 350 researchers and establish the Centre for Tissue Repair.

Method for expression of small RNA molecules within a cell
Analyzing messenger RNA and microRNA in the same reaction mixture
Methods and compositions for detection of small RNAs
Identification of microRNAs (miRNAs) in fecal samples as biomarkers for gastroenterological cancers
Method for determining the origin of a sample
RNA interference-mediating small RNA molecules

In Genome Research this week: methylation patterns in multiple myeloma, recent Y chromosome bottleneck, and more.

By studying the spectra of microbes on Earth, a team of researchers hopes to be better equipped to detect any on other worlds.

SolveBio's Mark Kaganovich says at TechCrunch that genomics needs an app to push it into the mainstream.

A University of Michigan team is using a Facebook app to recruit and keep in touch with participants in its 'Genes for Good' project.