Gene Silencing/Gene Editing

The data show that Phytophthora pathogens evolved effectors that bind to a conserved plant protein that controls small RNA biogenesis and processing.

The unique characteristics of mitochondrial genomes and diseases add a twist to the current discussions about heritable edits to the genome.

Though the edit was made in non-viable zygotes, the study wades into human germline engineering, a topic of great consternation for the CRISPR/Cas9 research community.

Thermo Fisher will market Horizon's X-MAN human haploid and diploid isogenic cell line collection. 

The firm adds CRISPR/Cas9 gene editing to its portfolio of plant genome engineering technologies, which also includes meganucleases and TALENs.

Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
Method for expression of small RNA molecules within a cell
Analyzing messenger RNA and microRNA in the same reaction mixture
Methods and compositions for detection of small RNAs
Identification of microRNAs (miRNAs) in fecal samples as biomarkers for gastroenterological cancers
Method for determining the origin of a sample

In Science this week: mtDNA analysis give glimpse into decline of Neanderthals in Europe, and more.

The University of Arizona's Raina Maier writes that an understanding of the Earth's microbiome is needed.

The proposed Canadian budget emphasizes partnerships with industry, Nature News reports.

An Australian study of personalized medicine has run into problems as it recruits patients.