Gene Silencing/Gene Editing

In the study, company researchers explored treating corn rootworms with RNAi molecules that would interfere with the viability of their offspring.

Editas will earn an upfront payment of $25 million to launch three research programs to apply CRISPR/Cas9 and TALEN genome editing to Juno's immunotherapies.

The bodies will assemble an international committee to guide future research and have planned a summit this fall for experts to discuss the implications of the technology.

Commercial software packages with a suite of additional features offer an alternative to academic guide RNA design tools for CRISPR/Cas9 genome editing.

High-throughput, systematic screens found 25 protein domains essential to AML, including six that are already drug targets in clinical trials.

Engineering and optimization of systems, methods, and compositions for sequence manipulation with functional domains
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
Method for expression of small RNA molecules within a cell
Analyzing messenger RNA and microRNA in the same reaction mixture
Methods and compositions for detection of small RNAs
Identification of microRNAs (miRNAs) in fecal samples as biomarkers for gastroenterological cancers

Heads of various research funding agencies discuss how to encourage scientific breakthroughs, ScienceInsider reports.

The Kansas City Star examines issues surrounding newborn genome sequencing.

Researchers say their Research Resource Identifier citation format is catching on, Nature News reports.

In Science this week: the Human Silencing Hub protein complex, and more.