Gene Silencing/Gene Editing

The House's Committee on Appropriations has added language to an FDA spending bill to prevent funds from being used to even evaluate germline editing experiments.

Bio-Rad scientist Jennifer Berman explains how ddPCR can help detect the basic efficiency of CRISPR/Cas9 and other genome editing technologies and more.

The scientists will use gut-on-a-chip technology to develop probiotics that can sense and respond to pathogenic microbes that have made their way into a person's GI  system.

The pipeline identifies interesting mutants with PCR and sequencing and allows the creation of multiplexed mutants.

Doudna and Baltimore lead a group of experts tasked with identifying issues to address at an international summit on human gene editing and a subsequent study.

RNA sequence-specific mediators of RNA interference
Engineering and optimization of systems, methods, and compositions for sequence manipulation with functional domains
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
Method for expression of small RNA molecules within a cell
Analyzing messenger RNA and microRNA in the same reaction mixture
Methods and compositions for detection of small RNAs

In PLOS this week: genomic analysis of Malaysian tuberculosis strain, database of bat genomes, and more.

An editorial appearing at The Scientist bemoans the high numbers of mitochondrial genome papers and suggests a different path for mitochondrial genome research.

Researchers and drug developers are excited about the potential of CRISPR-Cas9-based therapeutics, the Wall Street Journal reports.

US lawmakers want to develop a new incarnation of the National Children's Study, ScienceInsider reports.