Gene Editing & Gene Silencing | GenomeWeb

Gene Silencing/Gene Editing

A UC Berkeley team has found that C2c2 cuts RNA indiscriminately after being activated, a trait that could be leveraged to create diagnostics. 

Researchers are making mutations in a cell's genome to mark it and later read out that information to create cell lineage maps and chemical interaction histories.

Scientists led by Eric Kmiec showed that their strategy of point mutation editing with single-stranded DNA oligos and double-strand breaks works with CRISPR/Cas9. 

The ag-bio giant has landed a worldwide, non-exclusive licensing deal for agricultural applications of the genome-editing technology.

Horizon Discovery, Desktop Genetics, and Vectalys will work together to create fully-licensed, customizable kits for CRISPR/Cas9-based genetic screening.

Methods and products for expressing proteins in cells
Compositions and methods for gene silencing
Installation of genomes or partial genomes into cells or cell-like systems
Methods and compositions for gene inactivation
Protein having nuclease activity, fusion protein and uses thereof
Construction of new variants of dextransucrase DSR-S by genetic engineering

In Nucleic Acids Research this week: transcriptome patterns of Zika-infected cells, updated Comparative Toxicogenomics Database, and more.

BMJ study says that about half of former hematology-oncology regulators now work for industry.

Science should wish PhDs who leave academia well, a Nature editorial says.

New York-based doctors announce the birth of a baby boy whose parents underwent mitochondrial transfer therapy, New Scientist reports.