Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression.
Using absolute and relative gene expression analyses, researchers identified expression patterns associated with preeclampsia in dozens of placental tissue samples.
A renal cell carcinoma study revealed increased metabolic gene expression in PD-L1-positive tumors from individuals who did not respond to nivolumab.
Members of the International Cancer Genome Consortium identified four main groups of HER2-positive breast tumors using genome sequencing and expression arrays.
The method, developed by scientists at Uppsala University in Sweden, uses antibody-based proximity assays alongside off-the-shelf gene expression assays.
Array-based gene expression data suggests luminal and basal subtypes present in both human and canine forms of invasive urothelial carcinoma.
With virtual microdissection, the team tracked down stromal and tumor subtypes related to pancreatic patient outcome.
Clinicians at the recent ASCO noted that more practical and accurate molecular diagnostics are approaching the clinic alongside novel targeted drug regimens.
The investigators used the technique to identify two novel secretome targets and then confirmed them to be elevated in the blood of women with cancer.
The proof-of-principle application suggests networks of microRNA, RNA, and other 'omics data can untangle drug response and more.
Biomedical research projects are generating a ton of data that still needs to be analyzed, NPR reports.
Theranos is retiring some of its board members, including Henry Kissinger and George Shultz, Business Insider reports.
The heads of 29 scientific societies and some 2,300 researchers call on President-elect Donald Trump to rely on and support science in two separate letters.
In Science this week: genetically modified flu virus could be key to new live vaccines, and more.