gene expression arrays Oxford, Sanger Institute Researchers Draw on Gene Expression Testing for Sepsis Risk Algorithm Premium The algorithm distinguishes between groups of patients who are at high risk of developing severe illness and those who are low risk. Prostate Cancer Study Shows Oncotype DX GPS Test Accurately Measures Long-Term Outcomes Premium The 20-year study showed the test provided an accurate assessment of the risk of long-term metastases and mortality for patients with localized prostate cancer. Allarity Therapeutics Seeks FDA Premarket Approval for Prediction Tool as CDx for Dovitinib The DRP would be used to identify kidney cancer patients likely to benefit from dovitinib, a repurposed TKI for which Allarity plans to file an NDA this year. Type 1 Diabetes Onset Preceded by Gene Expression Changes Investigators identified natural killer cell-related expression signatures in blood samples from children who later developed type 1 diabetes or islet autoimmunity. Agendia FLEX Registry Powers Genomics Research on Underrepresented Breast Cancer Patients Premium FLEX will include full transcriptome data paired with 800 data points from 10,000 patients, offering researchers the chance to study diverse patient subsets. Nov 18, 2020 Agendia, Paige Partner to Codevelop New Assays Using MammaPrint, BluePrint Signatures Nov 9, 2020 Castle Biosciences Q3 Revenues Up 3 Percent Jul 10, 2020 Study Spells Out Immune, Genomic, Epigenomic Interactions in Hematological Malignancies Jun 12, 2020 New Data Support Role of Agendia BluePrint Test in Refining Breast Cancer Subtypes Premium Apr 22, 2020 Researchers See Immune, Age Contributors to Childhood Respiratory Virus Response Mar 9, 2020 Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance Jan 20, 2020 Multi-Disease Diagnostic Platform Project Receives €22.5M in EU Funding Dec 6, 2019 Local Coverage Determinations Roundup: Transplant Genomics, Opko Health Nov 11, 2019 Castle Biosciences Q3 2019 Revenues Quadruple Oct 18, 2019 10x Genomics Describes Capabilities of Visium Spatial Genomics Product Ahead of Release Premium Sep 3, 2019 Castle Biosciences Q2 Revenues Up 168 Percent Jun 24, 2019 Heart Failure Regulatory Gene Revealed in Tissue Transcriptome Study May 21, 2019 Agendia, Imegen Ink Distribution Deal for Breast Cancer Tests in Spain, Portugal May 2, 2019 Oral HPV DNA Persistence After Head and Neck Cancer Treatment Linked to Disease Progression Mar 25, 2019 Leukemia Relapse After Stem Cell Transplant Linked to Transcriptional Signature Jan 23, 2019 Genomic Differences in Pre-Invasive Lung Cancer Lesions May Predict Outcome Jan 8, 2019 Immunotherapy Prompts Shifts in Some Immune Cells Lacking Targeted Checkpoint Proteins Nov 27, 2018 Ovarian Cancer Cell Line Provides Clues to Recurring Mutations, Drug Sensitivity Oct 9, 2018 10,000 Immunomes Project Establishes Initial Baseline for Healthy Immune System Sep 25, 2018 Acute Sleep Deprivation Linked to Shift in Blood-Based Gene Expression Load More Breaking News Standard BioTools, SomaLogic to Merge Arima Genomics, Protean BioDiagnostics Launch 3D Genomics Cancer Testing Joint Venture Pathnostics UTI Test Nabs New York State Approval NanoString, A*Star, Next Level Genomics to Launch Spatial Biology Laboratory in Singapore FDA Approves Entrogen's RAS Mutation Detection Kit as CDx for Vectibix The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.