In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.
Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression.
Using absolute and relative gene expression analyses, researchers identified expression patterns associated with preeclampsia in dozens of placental tissue samples.
A renal cell carcinoma study revealed increased metabolic gene expression in PD-L1-positive tumors from individuals who did not respond to nivolumab.
Members of the International Cancer Genome Consortium identified four main groups of HER2-positive breast tumors using genome sequencing and expression arrays.
The method, developed by scientists at Uppsala University in Sweden, uses antibody-based proximity assays alongside off-the-shelf gene expression assays.
Array-based gene expression data suggests luminal and basal subtypes present in both human and canine forms of invasive urothelial carcinoma.
With virtual microdissection, the team tracked down stromal and tumor subtypes related to pancreatic patient outcome.
Clinicians at the recent ASCO noted that more practical and accurate molecular diagnostics are approaching the clinic alongside novel targeted drug regimens.
The investigators used the technique to identify two novel secretome targets and then confirmed them to be elevated in the blood of women with cancer.
In Science this week: metagenomic-based technique for determining protein structure, and more.
An academic laments the rise of narcissism in the sciences, the Guardian reports.
Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.
The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.