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gene expression analysis

Meeting presentations supported tweaking the clinical interpretation of Genomic Health's Oncotype DX and bolstered Biotheranostics' Breast Cancer Index.

A genome-wide association study that included two European cohorts pointed to a potential role for the SIGLEC15 gene in recurrent vulvovaginal candidiasis susceptibility.

The randomized data continue to distinguish Genomic Health's test for node-negative women, while new questions come to the fore node-positive disease and other areas of clinical care.

The researchers have used nCounter, an FDA-cleared platform from NanoString Technologies, to develop their gene expression assay for subtype classification.

The firm is conducting validation studies on its lung cancer test and continues to anticipate commercializing it in the second half of this year.  

The company's total revenue for the three months ended March 31 was $108.8 million compared to $92.6 million in the first quarter of 2018, exceeding analyst expectations.

The firm is using a microarray-based platform as part of a laboratory-based test to diagnose different types of stroke from blood samples.

Metascape uses data from over 40 knowledgebases and 10 model organisms to provide functional enrichment, interactome analysis, gene annotation, and membership search capabilities.

The firm's technology uses short oligo probes that target RNA directly on a pathology slide, allowing users to select regions of interest to profile.

Efforts highlighted at last week's AACR meeting included new efforts to advance gene expression signatures, improve PD-L1 tests, and calculate MSI across tumor types.

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Three genetic testing companies form a coalition to influence how Congress considers genetic privacy, The Hill reports.

University of California, San Diego researchers investigate how skin care products influence the skin microbiome, Scientific American reports.

The Wall Street Journal examines billing codes used by uBiome.

In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.