gene-environment interaction studies
Decode Genetics Study Unravels Complex Variant Effects on Blood Lipid Levels, Heart Disease Risk
Analyzing genetic contributors to lipid trait variance, researchers identified variant-variant and variant-environment interactions affecting coronary artery disease risk.
Breast Cancer Outcomes Show Ties to Neighborhood Income in New Study
In estrogen receptor-positive breast cancer patients, lower income appeared to track with higher tumor expression-based recurrence scores, and shorter survival in the low-risk RS group.
Study Follows Geographic Impacts on Apparent Heritability of Complex Traits
Using data for siblings and unrelated individuals from the UK Biobank project, researchers teased out geographic contributions to risk scores for dozens of complex traits.
Thyroid Size, Function in Children Linked to Nutrition-Related DNA Methylation Mark
A trial in Gambia suggests PAX8 gene methylation in 2-year-olds corresponds to thyroid volume, hormone production, and physical features later in childhood.
Schizophrenia Associated With Blood DNA Methylation Signature
Investigators tracked down a methylation signature in blood that corresponded with features found in postmortem brain samples from schizophrenia cases.