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gene editing

Promega said it will combine the CRISPR technology with its own products that are designed for knock-in of genetic reporters into cells or cell lines.

The partners are planning to integrate the technology into Horizon's research tools and services and to develop it for applications in cell therapeutics.

Which Way to Go

The New York Times reports on international efforts to oversee and regulate gene-editing work.

In Nature this week: study of gene drive feasibility in lab mice, circulating tumor DNA from cerebrospinal fluid to track glioma progression, and more.

Reuters reports that UK researchers are using gene-editing tools to develop flu-resistant chickens.

The nuclease, which comes from Bacillus hisashii, has gain-of-function mutations that facilitate robust editing in human cell lines and primary human T cells.

The protease-activated Cas9 enzymes could reduce off-target effects and could be used to sense pathogens and trigger an immune response.

The partners will work to find novel proteins, including DNA endonucleases, to develop new gene editing therapies for cystic fibrosis and other diseases.

An Associated Press poll finds that most US adults think it would be fine to use gene editing to prevent an incurable or fatal disease.

Watching CRISPR

The Los Angeles Times says CRISPR gene editing is a field to watch in the next year.

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Holden Thorp is to be the new editor-in-chief of Science and its related journals.

A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.

Adelaide University has suspended the head of an ancient DNA lab as its investigation of workplace bullying continues, Australia's ABC News reports.

In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.