gene editing

The firm's CEO Kevin Ness said confirmation of MAD7's editing activity in human HEK293T cells shows the potential for Inscripta's technology.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

Wellcome Sanger Institute researchers showed that Cas9-induced DNA breaks frequently resolved into deletions extending over many kilobases in the genome.

Researchers in the UK developed heritable Cas9-mediated mammalian genome editing that is acutely controlled by a cheap lysine derivative.

Researchers have used gene editing to reduce repetitive behaviors linked to autism in a mouse model of the condition, the Telegraph reports.

The Somatic Cell Genome Editing program was established earlier this year to help remove barriers from the adoption of genome editing for treating patients.

Risk With the Fix?

Two research teams warn that CRISPR-based gene editing could boost cancer risk by affecting p53 function, according to Stat News.

The approach generates a gRNA against a common genetic element called the flippase recognition target, making genome editing faster and scarless in E. coli.

The company — which was cofounded by David Liu, Feng Zhang, and Keith Joung — has licensed base editing technology from Harvard and the Broad Institute.

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A University of California, Los Angeles-led team has found turning off the CCR5 gene could improve recovery after a stroke, according to Scientific American.

South Dakota lawmakers are to weigh a bill aimed at teaching the strengths and weaknesses of scientific concepts, the Associated Press and KEVN-Black Hills Fox report.

In Science this week: the synthetic genetic system hachimoji, and more.

Thermo Fisher Scientific says it will no longer sell machines in China's Xinjiang region, according to the Wall Street Journal.