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gene editing

Even Earlier Edits?

NPR reports that researchers in New York are investigating whether it is possible to edit the genomes of human sperm.

At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The researchers identified genes that specifically extend the lifespan of neurons and found genes that increase the number of neurites in the brain.

The NAM, NAS, and Royal Society have formed a commission to develop a framework on the proper use of genome editing, and convened its first meeting in Washington, DC, this week.

In Nature this week: circular consensus sequencing method to sequence and assemble a human genome, a new CRISPR platform using the Cpf1 endonuclease, and more.

The team used this system to perform orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs.

Just Not on Yourself

A new California law would outlaw the sale of gene-editing kits without a label saying not to use it on yourself, Technology Review reports.

In Science this week: CRISPR gene editing and single-cell RNA sequencing together form a framework for studying genetic interactions, and more.

Investigators saw signs that risky TP53 missense mutations may interfere with wild type copies of the tumor suppressor gene in acute myeloid leukemia and other myeloid cancers.

In PNAS this week: emerging songbird pathogen Mycoplasma gallisepticum, CRISPR-Cas9-based knockdown finds role for lipoprotein transport in viability, and more.

Pages

Retraction Watch writes that a cancer researcher has had an eighth paper retracted.

Computational biologist James Taylor has died, according to Johns Hopkins University.

The Centers for Disease Control and Prevention is starting to test people for SARS-CoV-2 antibodies, according to the New York Times.

In PLOS this week: features of tumor-infiltrating immune cells, regulatory effects of SNPs associated with prostate cancer risk, and more.