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gene editing

As CRISPR technology continues to progress, some researchers are turning their focus to discovering or developing countermeasures and controls.

Researchers used the platform to identify small synthetic molecules that disrupt the editing activity of the SpCas9 nuclease.

Mismatch repair-deficient tumors with many insertion-deletion mutations and enhanced microsatellite instability responded better to anti-PD-1 immunotherapy.

Australia's ABC News looks into what's next after the country decides not to regulate some gene editing of plants and animals.

Australia will not be regulating gene editing of plants, animals, and human cell lines as long as no new genetic material is incorporated, reports Nature News.

The company launched last month with initial financing of $35 million and licenses to CRISPR and synthetic biology technology from the Broad and Harvard.

Researchers found that both CBEs and ABEs can cause transcriptome-wide RNA edits, which has implications for the research and therapeutic uses of base editors.

No Part

A Stanford University investigation finds that its researchers did not take part in He Jiankui's work to develop gene-edited infants.

NPR's Morning Edition reports that a number of CRISPR-based gene editing treatments are to be tested soon in humans in the US.

The team reported that engineering a hairpin secondary structure onto the spacer region of sgRNAs can increase specificity by several orders of magnitude.

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Researchers uncovered the HIV virus within a tissue sample collected in 1966, the Atlantic reports.

Nature News reports there are a handful of clinical trials underway to evaluate vaginal microbiome seeding of newborns born via caesarian section.

The Washington Post writes that humans may have contributed to the extinction of cave bears some 20,000 years ago.

In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.