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gene editing

The researchers identified genes that specifically extend the lifespan of neurons and found genes that increase the number of neurites in the brain.

The NAM, NAS, and Royal Society have formed a commission to develop a framework on the proper use of genome editing, and convened its first meeting in Washington, DC, this week.

In Nature this week: circular consensus sequencing method to sequence and assemble a human genome, a new CRISPR platform using the Cpf1 endonuclease, and more.

The team used this system to perform orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs.

Just Not on Yourself

A new California law would outlaw the sale of gene-editing kits without a label saying not to use it on yourself, Technology Review reports.

In Science this week: CRISPR gene editing and single-cell RNA sequencing together form a framework for studying genetic interactions, and more.

Investigators saw signs that risky TP53 missense mutations may interfere with wild type copies of the tumor suppressor gene in acute myeloid leukemia and other myeloid cancers.

In PNAS this week: emerging songbird pathogen Mycoplasma gallisepticum, CRISPR-Cas9-based knockdown finds role for lipoprotein transport in viability, and more.

The Plans

Science delves further into what other researchers knew about CRISPR scientist He Jiankui's plans, including his early-stage ideas for a clinic.

The Broad Institute called UC's new legal strategy "deeply unfortunate" and called on the university to "move beyond litigation."

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Researchers are sampling the wild relatives of modern crops to try to preserve genetic diversity, NPR reports.

MIT's Search for Extraterrestrial Genomes is developing sequencing tools to use to try to detect whether there is any life on Mars, Quartz reports.

Undark reports on a bill introduced this year to the US House of Representatives to strengthen scientific integrity.

In Genome Research this week: post-zygotic mutations in diabetes development, single-cell RNA sequencing study of aging, and more.