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gene editing

Scientists say that a DARPA project to use bugs to modify plant genes could be viewed as a bioweapon, the Associated Press reports.

Likely Allowed

New Japanese guidelines would allow for gene editing of human embryos for research purposes, according to Nature News.

In Nature this week: gene editing for tomato domestication, genome assemblies of inbred mouse strains, and more.

In Science this week: series of reviews about gene modification, and more.

For the first time, researchers used mitochondrially targeted zinc-finger nucleases to induce specific elimination of mutant mtDNA across the heart.

Under the terms of the agreements, Thermo Fisher obtains global non-exclusive rights to products, tools, and research services involving the technologies.

The firm said it saw a robust contribution in the first half of the year from its Dharmacon business and noted that it increased its reach into the US market.

The international team then used the approach to show that appropriate guide RNA design can reduce off-target effects of editing in mouse livers.

The researchers said their findings could help classify BRCA1 variants, particularly one whose impact on cancer risk is currently not clear.

A new study shows that DNA targets bound by nucleosomes are cleaved less efficiently than targets lacking nucleosomes, which could inform target selection.

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The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.

Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.

Washington Post columnist writes that she is skeptical about DNA-based diets.

In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.