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gene editing

China has ordered an investigation into claims that CRISPR was used to genetically modify two human infants, the Guardian reports.

Southern University of Science and Technology's He Jiankui has announced the birth of twin girls who underwent CRISPR-based editing of their CCR5 genes.

The Associated Press reports that gene-edited food may soon be for sale.

In Nature this week: machine learning-based method for CRISPR editing, symbiotic genes of Medicago truncatula, and more.

The investigators showed that template-free Cas9 editing is capable of repair to a predicted genotype, allowing for correction of disease-associated mutations.

DefiniGen said it plans to use ERS Genomics' technology to create disease models to support drug discovery for type 2 diabetes and other conditions.

The MIT team found that a previously uncharacterized Cas9 from Streptococcus canis has fewer PAM requirements than the more widely used S. pyogenes Cas9.

Use What We've Got

In a Nature opinion piece, the University of Michigan's Shobita Parthasarathy argues for the use of the patent system to regulate gene editing.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

Gene editing is expected to give rise to new job opportunities, according to BBC Capital.

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The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.

The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.

New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.

In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.