One team suggested Cas4 is required to assist the Cas1-2 complex, while the other said Cas4 helps maintain fidelity during CRISPR adaptation.
The startup was cofounded by the Broad Institute's Feng Zhang and Harvard's David Walt among others, and raised $15.6 million in June.
Pairwise, an agricultural startup using gene editing to address global food challenges, was cofounded by Feng Zhang, David Liu, and Keith Joung.
Genome editing will likely first touch many people's lives through its use in agriculture, says the University of California, Berkeley's Jennifer Doudna at the Financial Times.
A survey finds that the UK public approves of the use of gene editing to prevent genetic disorders from being passed down from parent to child.
The Financial Times reports that CRISPR-based biotechs are about to start human studies of gene-editing treatments.
In Science this week: CRISPR-based approach for recording cellular events, and more.
Whitehead Institute researchers were able to restore nearly full FMR1 expression in a fragile X syndrome iPSC cell line.
The CRISPR Journal has debuted its inaugural issue and, according to its publisher, plans to focus on research and commentary on gene editing.
Research teams and commercial firms are increasingly using genome editing to address farm animal health and welfare, from viral resistance to physical traits.
Nature News reports that researchers in Japan hope to soon test the use of reprogrammed stem cells to treat damaged corneas.
A new approach may help limit the number of fish that are mislabeled at markets or restaurants, according to New Scientist.
At Slate, the R Street Institute's Nila Bala discusses the privacy rights of suspects that genetic genealogy approaches in law enforcement bring up.
In PNAS this week: numerous mobile genetic elements contribute to Vibrio cholerae drug resistance, troponin I mutations in sudden infant deaths, and more.