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gene editing

The investigators showed that template-free Cas9 editing is capable of repair to a predicted genotype, allowing for correction of disease-associated mutations.

DefiniGen said it plans to use ERS Genomics' technology to create disease models to support drug discovery for type 2 diabetes and other conditions.

The MIT team found that a previously uncharacterized Cas9 from Streptococcus canis has fewer PAM requirements than the more widely used S. pyogenes Cas9.

Use What We've Got

In a Nature opinion piece, the University of Michigan's Shobita Parthasarathy argues for the use of the patent system to regulate gene editing.

This Week in Cell

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

Gene editing is expected to give rise to new job opportunities, according to BBC Capital.

Editing in the Womb

Researchers use a CRISPR approach in utero to treat a lethal condition in mice, Stat News reports.

Scientists say that a DARPA project to use bugs to modify plant genes could be viewed as a bioweapon, the Associated Press reports.

Likely Allowed

New Japanese guidelines would allow for gene editing of human embryos for research purposes, according to Nature News.

This Week in Nature

In Nature this week: gene editing for tomato domestication, genome assemblies of inbred mouse strains, and more.

Pages

The chief executive of the National Health Service in England is to call for tumor-agnostic drugs to be "fast-tracked," according to the Times.

Researchers in Australia are sequencing the Wollemi pine tree to try to protect it from extinction, Australia's ABC News reports.

Computerworld ranks Illumina as one of the top midsize organizations to work at in IT.

In Genome Research this week: links between biological aging and mutations affecting epigenetic regulators; long-read sequencing-based strategy to map chromatin accessibility; and more.