gel electrophoresis

The team's method utilizes two plasmids that produce DNA fragments from 50 to 1,000 bp, and are available through the nonprofit organization AddGene.

The partners plan to commercialize the system called Gly-Q for applications such as biotherapeutic cell line development. 

While the technology is not meant to replace mass spectrometry-based methods of PTM analysis, its developers said that it does offer a quicker, easier, and cheaper method to visualize modified proteins. Further, they added, the technology may eventually be used to develop diagnostic tools for diseases such as Alzheimer's, diabetes, and cancer.

Analyze This Proteome

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Two main technologies vie for the top protein analysis method spot. GT looks at the latest and greatest approaches for studying proteins.

Funding Update

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Recent NSF Awards in Proteomics and Protein Research

The World of DIY Bio

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Cloning in the kitchen? Sandra Porter checks out the DIYbio group and finds some great principles and some not-so-great biology.

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.