The perturbed genes will be identified by barcodes associated with single guide RNAs, and read using an in situ sequencing method.
More than 200 bone mineral density-linked loci turned up using data for over 140,000 individuals, including 153 new loci.
New research suggests some individuals with germline BRCA1/2 mutations who develop cancer may benefit from tumor BRCA functionality testing prior to treatment.
Nigel Mouncey joined the JGI in March from Dow AgroSciences and is interested in broadening the user base and scope of JGI's research.
In PNAS this week: functional genomic study of effects of anti-parasitic drugs, humped bladderwort genome assembly, and more.
The researchers reported that their assay could detect women with defective double-stranded break repair pathways even when sequencing could not.
A new user-friendly software tool is helping Rory Johnson of the University of Bern to do genome-wide screening of lncRNA function by deleting promoters.
The Finnish bioinformatics firm will aid European researchers and animal-focused diagnostics companies in developing a functional annotation of the dog genome.
Researchers working on the Human Functional Genomics Project have begun to unravel genetic relationships and variations in human immune response.
The so-called Cos-Seq method marries functional screening with next-generation sequencing to rapidly identify potential drug resistance mechanisms.
New Mexico is re-doing its proposed science education standards after criticism, the Associated Press reports.
Agbio executives say gene editing will speed up breeding efforts, according to the Wall Street Journal.
La Trobe University's Jenny Graves has won the $250,000 Prime Minister's Prize for Science, the Guardian reports.
In Cell this week: post-treatment changes to melanoma genome, multi-omics analysis of muscle-invasive bladder cancer, and more.