functional genomics
Osteoarthritis GWAS Leads to Key Genes, Treatment Targets
With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways.
Rare Variants in G Protein-Coupled Receptor Gene May Provide Protection From Obesity
The Regeneron Pharmaceuticals-led team also said that inhibiting the gene could represent a potential therapeutic strategy for obesity.
New ALS Risk Gene Suggests Role for Apoptosis
Rare variants in the TP73 gene affect protein function, increase apoptosis, and lead to the impaired development of motor neurons, according to a new study.
Fresh off a $43 million fundraising round, the drug discovery-focused bioinformatics firm is validating novel drug targets and compounds with an eye toward 2023 clinical trials.
Genomenon, Nostos Genomics to Integrate Technologies to Improve Rare Disease Dx
Genomenon will embed its Mastermind genomic search engine into the AI-driven Nostos AIon variant interpretation platform to power clinical decision support.