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functional genomics

Using genome-wide association study, cell line, organoid, and other data, researchers tracked down polygenic contributors to drug-induced liver injury in hepatocytes.

In animal models, loss of ALK was associated with protection from obesity, even when the animals were on a high-fat diet.

Functional genomics firm The DNA Company acquired digital therapeutics app My Pain Sensei, giving it an AI development platform and a Health Canada medical device license.

Exome sequences for nearly 35,600 cases and controls revealed genes prone to mutation in autism spectrum disorder, along with related cell types, functions, and developmental stages.

The researchers identified 240 metabolite-locus associations, including novel gene candidates for biotransformation and detoxification reactions.

A genome-wide association meta-analysis involving almost one million heart failure cases and controls identified 11 risk loci and helped distinguish potential causal contributors.

Researchers identified a new type 2 diabetes-associated site involving the ZRANB3 gene, which may have a role in regulating pancreatic beta cells.

Findings from a genome-wide association study suggest that fetal SNPs in SLIT2 and other genes may coincide with the risk of spontaneous preterm birth.

Multi-drug resistant Enterococcus faecalis isolates from a Wisconsin hospital contained independent mutations falling at overlapping resistance-related loci.

Researchers focused in on strong candidate genes in schizophrenia with brain anatomy, brain activity, and behavioral screens on a large set of zebrafish mutants.

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Two COVID-19 vaccine developers have released their trial protocols to build public trust, the New York Times reports.

A new analysis finds the rapid COVID-19 test from DnaNudge to be highly accurate, Reuters reports.

In Science this week: global citizens' assembly on genome-editing technologies proposed, epigenetic markers predict metformin response, and more.

According to the Verge, many US states are not including positive results from rapid COVID-19 testing in their case numbers.