functional genomics

This Week in PNAS

In PNAS this week: cautionary note for cross-species functional genomic comparisons, chimeric pig models of X-linked diseases, and more.

The company has yet to release formal studies, but discussed two cases that illustrate the potential benefit of the methodology in improving patient treatment.

The perturbed genes will be identified by barcodes associated with single guide RNAs, and read using an in situ sequencing method.

More than 200 bone mineral density-linked loci turned up using data for over 140,000 individuals, including 153 new loci.

New research suggests some individuals with germline BRCA1/2 mutations who develop cancer may benefit from tumor BRCA functionality testing prior to treatment.

Nigel Mouncey joined the JGI in March from Dow AgroSciences and is interested in broadening the user base and scope of JGI's research. 

This Week in PNAS

In PNAS this week: functional genomic study of effects of anti-parasitic drugs, humped bladderwort genome assembly, and more.

The researchers reported that their assay could detect women with defective double-stranded break repair pathways even when sequencing could not.

A new user-friendly software tool is helping Rory Johnson of the University of Bern to do genome-wide screening of lncRNA function by deleting promoters.

The Finnish bioinformatics firm will aid European researchers and animal-focused diagnostics companies in developing a functional annotation of the dog genome.

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Technology Review reports that 2017 was the year of consumer genetic testing and that it could spur new analysis companies.

A phylogenetic analysis indicates two venomous Australian spiders are more closely related than thought, the International Business Times reports.

In Science this week: CRISPR-based approach for recording cellular events, and more.

A new company says it will analyze customers' genes to find them a suitable date, though Smithsonian magazine says the science behind it might be shaky.