FISH
Developing Heart Atlas Established Using Gene Expression Profiles, Spatial Imaging
With single-cell transcriptomics and spatial mapping, researchers assembled a developing heart atlas used to define cardiac cell subpopulations, cellular interactions, and heart functions.
Medulloblastoma Long-Read Sequences Reveal Complex Rearrangements, Methylation Changes
With Oxford Nanopore sequencing, researchers found DNA methylation clues and complex rearrangement patterns that were subsequently assessed in a broader cancer set.
Oxford Gene Technology Obtains CE-IVDR Certificates for FISH Products
According to the Oxford, UK-based company, the probes are important for patient management while treating hematological cancers and prenatal conditions.
End-Stage Ovarian Cancer Marked by Rampant Treatment Resistance, Multiple Clones
By profiling multiple tumors per patient, researchers found pronounced polyclonal disease and diverse resistance mechanisms in end-stage high-grade serous ovarian carcinoma.
Extrachromosomal DNA Appears to Boost Cancer Adaptability, Impact Drug Response
Researchers demonstrated that random inheritance of extrachromosomal DNAs can boost cancer development, while helping a subset of tumor cells adapt to evade treatment.