FISH Extrachromosomal DNA Appears to Boost Cancer Adaptability, Impact Drug Response Researchers demonstrated that random inheritance of extrachromosomal DNAs can boost cancer development, while helping a subset of tumor cells adapt to evade treatment. Repeat Biomarker Testing Informs Next Steps for Treatment-Resistant EGFR-Mutant NSCLC Patients Premium Studies at ESMO showed the importance of repeat biomarker testing to guide treatment after resistance to AstraZeneca's Tagrisso, but tissue-based testing remains a hindrance. Vizgen Raises $85.2M in Series C Financing Vizgen plans to use the proceeds of the round to increase adoption of its hybridization-based Merscope spatial transcriptomics platform. Spatial Genomics Lays Off Two VPs, Other Employees Following $56M Fundraising The firm said last week that it planned to use the new funding to "aggressively expand" its workforce in both its technical and commercial organizations. Ikonisys Launches Next Generation of CTC Detection, Analysis Platform; Expands US Presence Premium Proceeds from a recent European public offering will fund commercialization of the French company's Ikoniscope20 platform in the US and EU. Apr 7, 2021 Vizgen Raises $37M in Series B Financing Apr 6, 2021 Applied Spectral Imaging, Kromatid Ink Global Comarketing Pact for FISH Probes Mar 5, 2021 Spatial Omics Firms Use AGBT as Launchpad for New Tech Premium Dec 30, 2020 Spatial Biology Interest, Products Mushroomed in 2020 Premium Dec 17, 2020 Merus, Sema4 Partner to Accelerate Enrollment in Zenocutuzumab Trial Dec 14, 2020 Startup Resolve Biosciences Readies Launch of Spatial Gene Expression Analysis Service Premium Sep 17, 2020 Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing Jul 27, 2020 Vizgen Plans Launch of Spatial Transcriptomics Platform Based on MERFISH Technology Premium May 29, 2020 Tumor Microbiome Appears to Vary With Cancer Type May 26, 2020 Takeda's Alunbrig Gets First-Line FDA Approval With Abbott CDx in ALK-Positive Lung Cancer Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Jan 30, 2020 Vizgen Launches With $14M Series A Financing Dec 10, 2019 KU-Led Team Begins Clinical Validation of Microfluidic Device for Leukemia MRD Detection Premium Oct 31, 2019 HER2 Amplification Confers Drug Sensitivity Across Tumor Types in New Study Premium Apr 22, 2019 Researchers Seek Best Approach to Identify Lung Cancer Patients With MET-Based Resistance Premium Mar 11, 2019 Enzo Biochem Fiscal Q2 Revenues Sink 26 Percent Feb 21, 2019 Genome Organization Variation Uncovered With Molecular Mapping Methods Nov 13, 2018 Angle to Enter NIPT Market With Rare Cell Isolation Platform Premium Sep 26, 2018 Cancer Genetics, Agilent Sign FISH Probe Supply Deal Mar 9, 2018 Johns Hopkins flowFISH Cytometry Assay Predicts Risk of Genetic Diseases Premium Load More Breaking News Bio-Rad Laboratories, Cytek Biosciences Partner on Flow Cytometry Reagents Tecan Inks Deals for NGS Library Prep System With Element Biosciences, Singular Genomics Genomenon, Flagship Biosciences Partner on Biomarker Discovery, Companion Dx Development Velsera to Integrate Arima Genomics Gene Fusion Test in Pierian Clinical Platform Evonetix Raises $24M in Extended Series B Funding Round The Scan Study Points to Tuberculosis Protection by Gaucher Disease Mutation A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds. SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource. Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages. UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.