exome sequencing Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Homozygous loss-of-function mutations in the BAG5 gene turned up in a subset of inherited DCM patients, and BAG5 appeared amenable to gene therapy in mouse models. Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found The researchers were able to reach a molecular diagnosis for about a third of their cohort, but that varied based on age, ancestry, and cardiomyopathy subtype. Analysis of Multi-Ancestry Cohort Uncovers Dozens of Genes Linked to Blood Lipid Levels The researchers conducted gene-based association testing of blood lipid levels in more than 170,000 individuals of various ancestral backgrounds. Variant Identified in Amish Population Appears to Protect From Cardiovascular Disease A rare missense variant in the enzyme-coding gene B4GALT1 is linked to lower coronary artery disease risk and reduced blood LDL cholesterol levels. Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups Researchers identified 12 multiple myeloma subgroups based on mutation, copy number, chromosomal rearrangement, and expression features in more than 650 tumors. Nov 3, 2021 Genomic Answers for Kids Team Releases Thousands of Genomes to Gain Insights Into Rare Diseases Premium Oct 28, 2021 Kidney Cancer Study Links Checkpoint Immunotherapy Responses to T Cell Features Oct 22, 2021 SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes Oct 20, 2021 Rady Children's Team Presents Genomic Medicine Management Tool at ASHG Oct 19, 2021 Exome Sequencing of UK Biobank Participants Highlights Natural Variation, Gene Function Oct 19, 2021 De Novo Mutations Linked to Male Infertility in Trio Exome Sequencing Study Oct 13, 2021 Mayo Clinic, Personalis Ink Comprehensive Genomics Research Collaboration Sep 30, 2021 Sequencing Study Points to Prenatal Development Syndrome, Possible Treatment Strategy Sep 14, 2021 Centenarian Exome Analysis Points to Conserved Longevity Pathways Sep 9, 2021 Blueprint Genetics to Analyze Biobank Samples for Rare Diseases in New Finnish Study Sep 7, 2021 Centogene Q2 Revenues Continue to Benefit From COVID-19 Testing as Core Business Starts to Recover Aug 18, 2021 Helix Study Identifies Additional Genes for Population Genetic Screening Premium Aug 12, 2021 Benign Hypertension-Causing Tumors Linked to Somatic Codriver Mutations Aug 11, 2021 Sema4, Avera Health Collaborate on Precision Oncology Program Aug 5, 2021 Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype Jul 28, 2021 AbbVie, Biogen, Pfizer Join With Broad Institute on Genebass Exome Variant Project Premium Jul 9, 2021 Integrated Tumor, Microbiome Features Influence Immunotherapy Combo Effects in Advanced Melanoma Jul 9, 2021 Human Reference Genome Choice Impacts Variant Calling, but Switching Is Tricky Premium Jul 7, 2021 Rare Mutations Associated With Significantly Higher Risk of Type 2 Diabetes in New Study Jul 6, 2021 Imputation of UK Biobank Data Uncovers Rare Coding Variants Linked to Range of Traits Load More Breaking News In Ongoing False Advertising Suit, Judge Allows Natera Counterclaims Against Guardant Health Centogene Strikes Rare Disease Target Discovery Deal With Insilico Medicine Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution The Scan Transplant Tests Edited Pig Kidneys The Associated Press reports a University of Alabama-Birmingham team transplanted genetically modified pig kidneys into a brain-dead human patient. UK Changes Some Gene-Edited Crop Rules A new law may enable gene-edited crops to be sold in the UK within about five years, New Scientist says. Pill Works Against Omicron in Lab Pfizer's antiviral pill to treat SARS-CoV-2 appears to work against the Omicron variant, the Wall Street Journal reports. Nature Papers Find Genetic Risk Factor for Smell, Taste Loss in COVID-19; Analyze TB Granulomas In Nature this week: genome-wide association study find locus linked to the risk COVID-19 patients losing their sense of taste or smell, and more.