exome capture

Qiagen intends to use System Biosciences' ExoQuick technology in its precipitation-based miRcury Exosome Kits.

Many genes are poorly covered or not covered at all by exome sequencing, which could lead to false negatives in clinically relevant genes.

NEW YORK (GenomeWeb News) – A Memorial Sloan-Kettering Cancer Center-led team has taken an exome- and genome-sequencing centered look at the mutations that may be found in the salivary gland cancer adenoid cystic carcinoma, or ACC.

NEW YORK (GenomeWeb News) – Two studies published this week are offering a look at the genetics behind meningioma, a type of primary central nervous system tumor.

NEW YORK (GenomeWeb News) – Elevated schizophrenia risk appears to stem from a preponderance of deleterious de novo mutations, including recurrent mutations to a handful of potential risk genes, according to an exome sequencing study appearing online today in Nature Genetics.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Cofactor Genomics and Intrepid Bioinformatics have partnered to integrate their offerings for analyzing cow genome data, St. Louis-based Cofactor said today.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Caliper Life Sciences announced today a deal with the Center for Genome Analysis at Yale University to implement protocols for exome capture and library preparation workflows.

The University of Washington team reported on a hybrid assembly that combines mapping to a reference genome with local de novo assembly. The study was presented during this month's Biology of Genomes meeting in Cold Spring Harbor, NY.

So far, the Broad Institute has used the v2 kit to sequence the exomes of more than 5,100 human samples "from a variety of cancer and heritable disease studies."

Pages

Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.