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epigenetics

New Algorithms Enable Direct Nanopore-Based Detection of Additional RNA Modifications
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The method was used to analyze two epigenetic modification types that were previously undetectable with Oxford Nanopore sequencing.

CRISPRoff Reversible Epigenome Editing Method Could Enable Safer, More Precise Therapeutics
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UCSF and MIT researchers have developed a way to edit the epigenome and then completely reverse the changes, when needed.

OncoDiag Taking Aim at Broader Adoption of Molecular Multiplex Test for Bladder Cancer Recurrence
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On the back of a recently announced $3 million in funding, the firm has begun marketing its Urodiag kit to urologists throughout Europe.

Grail Cancer Early Detection Test Performance Holds Steady as Q2 Launch Approaches
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Recent results from the firm's case-control study cohort showed overall sensitivity of about 50 percent but higher performance for a subset of high-mortality cancers.

Delfi Diagnostics Starts Prospective Lung Cancer Screening Trial

The company is planning to commercialize its cancer early detection technology initially in lung cancer and is working with NYU researchers to explore future expansions.

Mar 24, 2021

DARPA Programs Leveraging Host-Response Testing, CRISPR for Future Pandemic Preparedness
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Feb 3, 2021

Human Epigenome Map Reveals New Insights Into Genetic Loci for Traits, Diseases

Jan 12, 2021

Delfi Diagnostics Details Plans to Advance Fragmentomic Method for Early Cancer Detection
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Jan 12, 2021

Delfi Diagnostics Nets $100M in Series A Financing, Plans Multi-Cancer Screening Test

Jan 11, 2021

Multi-Cancer Molecular Screening Assays Primed for Clinical Implementation in 2021
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Jan 5, 2021

VolitionRx, 4D Lifetec Partner to Combine Early Cancer Detection Assays

Dec 2, 2020

Epigenome Study Maps Hydroxymethylation Across Diverse Human Tissue Types

Nov 2, 2020

Bluestar Genomics Eyes Pan-Cancer Early Detection With Epigenetic Assay Technology
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Oct 30, 2020

Qiagen, Phase Genomics Ink US Licensing Agreement for Hi-C Sequencing Technology

Oct 14, 2020

Epigenomic Study of Brain Development Uncovers Cell Type-Specific Regulatory Programs

Sep 28, 2020

Alzheimer's Disease Linked to Epigenetic Changes in Multi-Omic Study

Sep 16, 2020

Illumina's Stock Falls 9 Percent on Grail Acquisition Rumors

Sep 16, 2020

Epigenetic Markers Predict Type 2 Diabetes Patients Who Respond to, Tolerate Metformin

Sep 15, 2020

Pancreatic Cancer Treatment Clues Uncovered From Genomic, Chromatin Profiles

Sep 9, 2020

10x Genomics to Sell 3.5M Shares in Public Offering

Jul 31, 2020

Data Supports Singlera's PanSeer Test as Company Narrows Focus to Colorectal Cancer Detection
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Jul 24, 2020

Norwegian Diagnostics Firm Age Labs to Develop Epigenetics-Based Test for SARS-CoV-2
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Jul 2, 2020

Translation of Dog Years Into Human Years Updated With Epigenetic Analysis

Jul 1, 2020

AnchorDx Demonstrates Liquid Biopsy DNA Methylation Test for Early Cancer Detection
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Jun 24, 2020

Stanford Team Debuts EPIC-Seq Method to Detect, Classify Cancer From cfDNA Fragment Patterns

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The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.