Researchers used genomic approaches to delve into the cleft lip and palate-related functions of a transcription factor called p63, identifying key enhancer and chromatin interactions.
The clinical genome-wide DNA methylation test can diagnose genetic diseases that are missed by exome or genome sequencing and evaluate variants of unknown significance.
Researchers identified blood lipid-associated adipose tissue methylation marks with an epigenome-wide association study on obese individuals undergoing bariatric surgery.
The team engineered an enhanced Acidaminococcus sp. Cas12a variant that has the ability to target many previously inaccessible protospacer adjacent motifs.
The JHU technology leverages an epigenetic biomarker panel and a sponge-on-a-string collection device, as well as a PCR-based method, to detect Barrett's esophagus.
The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.
