electron microscopy

A Salk Institute-led team developed an approach to visualize chromatin in vivo and used it to examine the organization of DNA in interphase and mitotic cells.

Under the terms of the collaboration, the firms will combine ZS Genetics' proprietary technologies with HTA's experience in high-resolution electron microscopy.

The company said FEI's technology will complement its mass spectrometry business, particularly in its work on structural proteins and biopharmaceuticals.

Using this technology, scientists were able to visualize BRCA1 protein interaction in a near-native environment and gain insight into its mechanics.

The study published in Science revealed a thumb-like protein domain that recognizes and cleaves a single-stranded RNA.

A study in Science describes a novel function for a protein in which it specifies for long, random chains of alanine and threonine to be added to stalled proteins. 

The company uses heavy atoms to label individual bases and an electron microscope to disinguish between each base.

NEW YORK (GenomeWeb) − Researchers in Toronto have developed a method to dissect and sequence DNA from structures within the nucleus of individual cells, allowing them to study the spatial arrangement of genes in great detail.

Scientists formerly employed by electron microscopy sequencing firm Halcyon Molecular have published a method they developed at the company for stretching single DNA strands and placing them on a substrate.

ZS Genetics has started to work on a prototype of its transmission electron microscopy-based DNA sequencer that it hopes to complete next year, followed by the release of a commercial instrument several years later.

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Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.

Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.

In Science this week: gut microbiome influences liver cancer growth, spread; and more.