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drug metabolism

A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.

The new distribution partnership is for the US acute care market where, until now, Spartan was selling directly.

The trial aims to combine personal information, pharmacogenomics data, and machine-learning tools to select the best anti-seizure medication for patients. 

 

 

The system relies on the use of scannable safety code cards containing patient data, along with a web portal and automated analysis tools that deliver customized diagnostic reports.

The firm will launch two new analysis modules for its Genetic Information Management Suite next year, in addition to a new pharmacogenomics mobile application.

Results from a randomized clinical trial known as GIFT suggest that genotype-guided warfarin dosing is linked to fewer adverse events than clinical dosing.

Data from several large cohorts suggests that a variant in LILRB5 may produce a propensity for muscle pain or myalgia, upping the risk of statin intolerance.

The effort is already bearing fruit, as the team has been able to validate several variants known to be connected with adverse drug reactions.

In Cell this week: host-microbe interactions and cancer drug response; links between transcription rate, mRNA translation, and methylation; and more.

A study led by researchers from Brigham and Women's Hospital on the effect of CYP2C19 testing on physicians' prescribing patterns has found that when doctors received patient test results for genetic markers associated with clopidogrel response through a pharmacy-benefit manager-

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Researchers report on a concerning strain of the H1N1 swine flu virus found among pigs in China, Agence France Presse reports.

Science reports that a new White House Office of Management and Budget memo rescinds previous ones that helped research institutions deal with pandemic-related closures.

The Associated Press reports that US officials are considering allowing pooled COVID-19 testing.

In Genome Research this week: Y chromosome gene expression analysis, de novo mutations rise with paternal age in rhesus macaques, and more.