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drug metabolism

Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response
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Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs.

Microbiome Metabolite Screening Method Uncovers Gut Microbe-Drug Interactions, Variability

A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.

Spartan Bioscience Taps Cardinal Health as US Distributor of CYP2C19 Genotyping Assay

The new distribution partnership is for the US acute care market where, until now, Spartan was selling directly.

Kailos Genetics, Doc.ai Partner With Stanford on Epilepsy Digital Health Trial
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The trial aims to combine personal information, pharmacogenomics data, and machine-learning tools to select the best anti-seizure medication for patients. 

 

 

European Clinics Evaluating New Card System for Making PGx Data Available to Patients
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The system relies on the use of scannable safety code cards containing patient data, along with a web portal and automated analysis tools that deliver customized diagnostic reports.

Nov 28, 2017

Bio.logis Readies New Clinical Genetic Data Interpretation Tools Amid Growing Customer Interest
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Sep 26, 2017

Genotyping Appears to Offer Warfarin Dosing Edge in New Clinical Trial

Aug 30, 2017

Common Variant Implicated in Statin-Related Muscle Aches

Jul 12, 2017

Estonian Team Pairs Pharmacogenomics, EHRs to Reduce Adverse Drug Reactions
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Nov 20, 2013

In Prescribing Study, Few Doctors Altered Treatment for Poor Plavix Metabolizers Based on Genotype
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Oct 23, 2013

Genewiz to Launch Clinical Versions of PGx and Cancer Panels Starting This Year
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Sep 24, 2013

Luminex CYP2C19 Assay Cleared by FDA, CE Marked in Europe

Aug 27, 2013

UPDATE: Spartan Bioscience Gets FDA OK for Rapid CYP2C19 Assay

Jul 15, 2013

Luminex Gets FDA OK for New Version of CYP2D6 Kit

Mar 26, 2013

Startup Twistnostics Developing Rapid Microarray Platform for PGx and Infectious Disease Assays
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Jan 30, 2013

FDA Clinical PGx Guidance Pushes Early Consideration of Genomic Data in Drug Research
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Sep 13, 2010

AB Sciex, Univ. of Melbourne to Develop Mass Spec Approach for Metabolism Studies

Apr 28, 2009

New Product Watch: Apr 28, 2009
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Apr 22, 2009

New Releases: Apr 22, 2009
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Apr 7, 2009

After Inking Distribution Deal with Thermo, Osmetech Plans New Tests, Financing Rounds
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Mar 17, 2009

Looking to Refocus on Core Array Business, Affy Transfers CLIA Lab to Navigenics
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Feb 20, 2009

AZ, Cellartis Extend Alliance Developing hESC-Derived Liver, Heart Cells
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Feb 16, 2009

XenoTech to Use Waters Synapt HDMS System for Metabolomics Services

Breaking News
The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.