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drug development

The draft guidance provides non-binding recommendations on ways to use genomic information in early-phase drug development.

The deal combines TGen's molecular analysis tools with Flagship's expertise in high-throughput immunohistochemistry to support preclinical drug development and human clinical trials.

Early studies involving a monoclonal antibody against PCSK9 show promise in lowering LDL in hypercholesterolemia patients. According to at least one published study, Pfizer is investigating assay methods for monitoring treatment response by gauging PCSK9 levels.

Clinical Data, which at one point was working toward becoming a personalized medicine company, is now "considering the sale of its genetic testing and biomarker development business."

PGx & molecular Dx

The firm also said that it and NextGen Sciences have developed a protein biomarker assay method that can provide rapid, reproducible, quantitative measurement of protein expression in formalin-fixed, paraffin-embedded tissue.

Although the Pharmacogenomics Training and Research Laboratory will primarily focus on training students in the discipline, it could also enable R&D partnerships with industry players.

Snippets: Apr 22, 2009

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Johns Hopkins University's Genetics and Public Policy Center, National Cancer Institute, Santoris, RayBiotech

The new budget and stimulus funds will fuel the Genome Atlas, a personalized medicine platform, and more grants to young investigators.

The new unit will be headquartered in San Diego and led by Arthur Levin, chief development officer of Denmark-based Santaris.

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NPR says the explosion and fire earlier this week at a Russian lab that stores dangerous pathogens revives the question of whether such samples should be kept.

According to Wired, Nebula Genomics is providing a way for people to get their genomes sequenced anonymously.

A 26-year-old woman tells Cosmopolitan about learning her APOE status at a young age.

In Science journals this week: a functional genomic screen uncovers drug combination that increases KRAS inhibitor efficacy in aggressive lung cancer, and more.