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drug development

The Jamaican Lion strain was sequenced and assembled with DASH funding, and will be published via "crypto-incentivized, blockchain-recorded peer review."

Genetic and phenotypic data for Million Veteran Program participants led to loss-of-function changes in a gene inhibited by cilostazol.

Organizers of a data analysis challenge remain hopeful that a recent update to the Connectivity Map resource will lead to breakthroughs in DILI detection by next year.

Backed by Andreessen Horowitz and Polaris Partners, Camp4 hopes its high-resolution gene maps can shorten and remove risk from the drug development process.

Saturation mutagenesis of the human malaria parasite Plasmodium falciparum identified almost 2,700 essential genes during the blood stage of infection.

By sequencing and characterizing the genome of Artemisia annua, researchers uncovered gene expansions and regulatory features linked to artemisinin production.

With multiple independent biomarkers, and potential combinations that may require even more subtyping, diagnostics to guide immunotherapy appears to be getting more complicated.

Datavant, a fledgling spinoff from Roivant Sciences, is trying to break down information silos that often lead to poorly designed clinical trials.

Bioage Labs now intends to set up an internal laboratory to experiment with different compounds, while building out its team.

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In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Science reports a new US defense bill would establish two groups aimed at combating foreign influence on research. 

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.