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droplet-based PCR

10x asked the US District Court for the Northern District of California to dismiss a suit, while another district court judge denied a 10x motion to dismiss.

The new chip enables the firm's digital PCR system to test up to 240 samples per day, and also uses lower volumes of sample input. 

The company acquired GnuBio, which was developing a droplet-based sequencing platform, in 2014 for $39.7 million in cash and $10 million in contingent payments. 

The sales decline was largely due to a slowdown in productivity related to the recent launch of the company's global enterprise resource planning system in Western Europe.

A proof-of-principle study has shown a new qPCR device can detect bacterial DNA in under four minutes using droplet size as a readout of amplification.

The company has established a streamlined workflow that customizes and automates key steps of the sample prep process.

The simple, semi-open format uses a microfluidics robot to generate an array of picoliter droplets on a reusable chip. 

The test, which is being developed with a National Science Foundation grant, is based on a novel PCR technology that doesn't require traditional instrumentation.

Researchers from University College London, have shown that a targeted bisulfite sequencing method using RainDance Technologies' microdroplet PCR system can accurately measure DNA methylation levels at sample sizes as low as 100 nanograms.

Researchers from Northwestern University and the University of Chicago have demonstrated in a new study that droplet-based digital PCR offers the ability to detect BCR-ABL1 fusion transcripts with a lower limit of detection and quantification than currently used quantitative PCR

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The US has sent its formal notice of withdrawal from the World Health Organization, according to the Wall Street Journal.

Science reports that a draft spending bill would increase the US National Institutes of Health budget by 13 percent.

The Harvard Crimson reports that Harvard and MIT are suing the Department of Homeland Security and ICE over the new international student visa policy.

In Nucleic Acids Research this week: algorithm to determine molecular sequence types and other microbial features, computational method to uncover R-loop structures, and more.