DNA purification

A recently published research paper has shined a spotlight on the potential for manufactured sample prep products to harbor contaminating DNA sequences that can confound the results of highly sensitive molecular detection techniques such as next-generation sequencing, especially

A team from the University of Washington has developed a device that uses nanotips and electric field manipulation to concentrate and extract DNA from biological samples for subsequent PCR or other analysis.

MacConnell Research has been awarded $483,000 by the National Institutes of Health for the first year of a two-year project to ready a low-cost, cassette-based automated DNA purification technology for commercialization.

Lawrence Berkeley National Laboratory has made available for licensing a DNA extraction and isolation method that its inventors claim is more efficient, sensitive, and selective than current commercial DNA extraction kits.

Diffinity Genomics said this week that it has closed a Series B financing.

Diffinity Genomics said this week that it has signed a non-exclusive agreement with Sigma-Aldrich to distribute the Diffinity RapidTip PCR purification product worldwide.

Boreal's prototype platform can differentiate and enrich for sequences that differ by one nucleotide from as many as 10,000 copies of background DNA. The company believes it has potential for use in clinical applications.

OriGene gains products for DNA and RNA purification and multiplex assays for genotyping, microRNA profiling, and transcription factor activity analysis.

The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.