DNA purification

Circulomics, Bionano, Sage Science, RevoluGen, and others have been developing methods for extracting DNA hundreds of kilobases and up to megabases in length.

New research suggests that the physicochemical changes to DNA in a cancer-related methylation landscape can alter a DNA molecule's affinity for gold substrates.

A recently published research paper has shined a spotlight on the potential for manufactured sample prep products to harbor contaminating DNA sequences that can confound the results of highly sensitive molecular detection techniques such as next-generation sequencing, especially

A team from the University of Washington has developed a device that uses nanotips and electric field manipulation to concentrate and extract DNA from biological samples for subsequent PCR or other analysis.

MacConnell Research has been awarded $483,000 by the National Institutes of Health for the first year of a two-year project to ready a low-cost, cassette-based automated DNA purification technology for commercialization.

Lawrence Berkeley National Laboratory has made available for licensing a DNA extraction and isolation method that its inventors claim is more efficient, sensitive, and selective than current commercial DNA extraction kits.

Diffinity Genomics said this week that it has closed a Series B financing.

Diffinity Genomics said this week that it has signed a non-exclusive agreement with Sigma-Aldrich to distribute the Diffinity RapidTip PCR purification product worldwide.

Boreal's prototype platform can differentiate and enrich for sequences that differ by one nucleotide from as many as 10,000 copies of background DNA. The company believes it has potential for use in clinical applications.

OriGene gains products for DNA and RNA purification and multiplex assays for genotyping, microRNA profiling, and transcription factor activity analysis.

Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

John Mendelsohn, a former president of the University of Texas MD Anderson Cancer Center, has died, the New York Times reports.

Identical twins receive different estimates of ancestry from the same direct-to-consumer genetic testing firms, CBC reports.

In PNAS this week: chromosomal features of maize, adaptations in the vinous-throated parrotbill, and more.