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digital PCR

Researchers are using Bio-Rad's droplet digital PCR technology to validate seven ctDNA biomarkers that may predict melanoma recurrence.

A University of Michigan Health System team showed that heat fragmentation leads to increased detection of a G-to-A mutation of the KRAS gene in vendor-purchased DNA.

Two Boston-based researchers shared methods for detecting circulating nucleic acid biomarkers for potential use in cancer diagnosis and monitoring.

Bio-Rad reported $570.6 million in revenues in Q4, a 5 percent drop year over year but a 3 percent increase on a currency-neutral basis.

Digital PCR can better detect low levels of chronic myeloid leukemia in patients than other PCR-based approaches, according to Imperial College London researchers.

A majority of respondents said liquid biopsy is poised to become a widely used tool for assessing cancer mutations within the next one to four years, with NGS-based analysis preferred over other testing modalities.

This Week in Science

In Science this week: issues in reproducibility, circulating DNA predicts breast cancer relapse, and more.

The company filed to go public in March with plans to offer up to $60 million of its stock. 

The firm said that it plans to list its stock on the Nasdaq under ticker symbol "RAIN" and added that its 2014 revenues were up 78 percent year over year to $30.6 million.

The new RUO application for the company's QuantStudio 3D Digital PCR platform is designed to enable researchers to accurately phenotype the CYP2D6 gene, a key indicator of drug metabolism.


In PLOS this week: role for Notch signaling in congenital heart disease, sciatica risk variants, and more.

Researchers in China have used the CRISPR/Cas9 genome editing approach to alter the length of hair fibers in cashmere goats.

According to ScienceInsider, the Scripps Research Institute and the California Institute for Biomedical Research are merging.

National Cancer Institute researchers didn't report severe adverse events to Food and Drug Administration in a timely manner, the Wall Street Journal reports.