CRISPR

Risk With the Fix?

Two research teams warn that CRISPR-based gene editing could boost cancer risk by affecting p53 function, according to Stat News.

In exchange, Editas has the exclusive right to be the first to negotiate for licenses to genome-editing inventions that arise from the sponsored research.

The approach generates a gRNA against a common genetic element called the flippase recognition target, making genome editing faster and scarless in E. coli.

By combining iPSCs, CRISPR gene editing, and transcriptomic approaches, researchers examined the effects of an Alzheimer's disease risk variant on brain cells.

Three CRISPR researchers are to receive the Kavli Prize in nanoscience, according to the Associated Press.

The NMI Natural and Medical Sciences Institute at the university and its affiliate will use the patents to expand their cell-based research service offerings.

By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.

This Week in Nature

In Nature this week: genome-wide CRISPR-Cas9 screen finds key cell surface receptor used by the chikungunya virus, and more.

The company — which was cofounded by David Liu, Feng Zhang, and Keith Joung — has licensed base editing technology from Harvard and the Broad Institute.

Biohacking Worries

The New York Times reports that biohackers are also concerned about the potential harms of DIY genetic engineering.

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A new report highlights the potential threats posed by advances in synthetic biology, NPR reports.

Johns Hopkins University's Steven Salzberg and his colleagues have come up with a new estimate for the number of human genes, Nature News reports.

A Bloomberg reporter tried to get her genetic data deleted, but found it's not so simple to do.

In Genome Research this week: study of intra-tumor heterogeneity, workflow resources for EPIGEN-Brazil, and more.