CRISPR

Drive Resistance

Gene drives might run into biological resistance, the Economist reports.

This Week in Science

In Science this week: full CRISPR locus integration complex structure, and more.

Researchers led by Jennifer Doudna found that the architecture of the Cas1-Cas2 integrase contributes to bacterial adaptive immunity.

The team said the resource allows for single-target or combinatorial genetic screens to be carried out at scale in a multiplexed or arrayed format.

The group will study the potential risks and benefits of using CRISPR/Cas9 to develop gene drive systems for control and manipulation of mosquito populations.

The firm recently released two droplet digital PCR-based assays that can characterize edits generated by CRISPR-Cas9 or other genome editing tools.

Galloping Horse

Harvard University's George Church and his colleagues encoded a GIF into a bacterial population.

This Week in Nature

In Nature this week: bacteriophage evolution varies based on host, lifestyle, and genetic factors; and more.

A new study led by UC-Berkeley scientists shows that an inhibitor protein from a Listeria bacteriophage can block Cas9 from interacting with DNA.

The company said it will use the funds to develop antimicrobial therapeutics based on CRISPR-Cas3 technology.

Pages

Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.