CRISPR

The team reported that its coordinated formation of paired single-stranded DNA breaks yielded higher frequencies of accurately edited cells.

The team found that a protein called OCT4 was necessary for the correct formation of a blastocyst in the first few days of embryonic development.

A Butterfly's Wings

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

The team used CRISPR to inactivate a gene in colon organoids, and found that a specific DNA repair defect underlies a mutational signature in some cancers.

PacBio is refining the CRISPR/Cas9 capture technique with several early- access sites and plans to launch it more broadly in 2018.

The investment bank began coverage with an Outperform rating, noting that Horizon's recent acquisition of Dharmacon is highly complementary and synergistic.

The team aims to release the new resource sometime next year, with the hope that it will become as widely used as other institute databases.

The researchers used this approach to show how non-coding variation associated with human immune dysfunction alters context-specific gene programs. 

The La Jolla, California-based firm is moving beyond its US home market into other regions that promise growth for synthetic genomics providers.

Doudna will get $2.1 million to set up the Center for Genome Editing and Recording, and Zhang will get $1.1 million to develop tools for RNA interrogation.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.