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CRISPR

UCSF's test, developed with Mammoth Biosciences, uses CRISPR technology, while the tests from the Broad Institute and BioSewoom are PCR-based.

Unlike previously described cytidine deaminases, this toxin catalyzes the deamination of cytidines within double-stranded DNA, the researchers said.

Using computational modeling, researchers developed tools that they said will facilitate modeling and correction of genetic diseases by base editing. 

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.

The companies will combine the Binx io diagnostic platform with Sherlock Bio's CRISPR technology to create an easy-to-use rapid test for the point of care.

At the second virtual session of the AACR annual meeting, researchers also discussed how they're using CRISPR to develop better cancer models and reprogram T cells.

NPR reports that the first person in the US to undergo a CRISPR-based treatment for sickle-cell disease continues to do well nearly a year after treatment.

Christiana Care researchers have identified a unique protospacer adjacent motif site that allows them to knock out the NRF2 gene in tumor cells while leaving normal cells alone.

In Science this week: multiple SARS-CoV-2 introductions into Northern California and the development of the 'very fast CRISPR' method.

The technique could be used to study DNA repair at high resolution in space, time, and genomic coordinates, the researchers said.

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Researchers have developed a robotic lab assistant, the Verge reports.

CBC News reports Canada's Supreme Court is to rule on the constitutionality of the country's genetic non-discrimination law today.

The Associated Press reports the World Health Organization is sending experts to China to investigate the animal source of SARS-CoV-2.

In Science this week: atlas of affected cell populations in idiopathic pulmonary fibrosis, and more.