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CRISPR

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

Dan Rather, the former CBS Evening News anchor and executive producer of a new documentary, writes at the Guardian that everyone needs to know about CRISPR.

In PNAS this week: analysis of FOXA1 upregulation in ER-positive breast cancer, gene editing to correct recessive dystrophic epidermolysis bullosa, and more.

The company said it will use the funds to accelerate the development of applications for its Onyx Digital Genome Engineering platform.

The new tool can provide a more accurate and unbiased view of the multiple outcomes of CRISPR-based gene editing, according to the developers.

The Human Protein Atlas was founded in 2003 to map all the human proteins in cells, tissues, and organs using a variety of omics technologies.

Claims and Data

MIT's Technology Review has published excerpts from researcher He Jiankui's unpublished manuscript describing how he edited the genomes of twin girls as embryos with commentary.

Little Known

The Associated Press gives a rundown of what little is known about He Jiankui and the twin girls since his announcement last year that he had edited their genomes as embryos.

A bioethicist from Abertay University uses a utilitarian approach to justify genetically modifying the human germline, the BBC reports.

Functional enhancers can accompany oncogenes on the circularized extrachromosomal amplicons found in glioma and other tumors, enhancing cancer growth.

Pages

In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Science reports a new US defense bill would establish two groups aimed at combating foreign influence on research. 

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.