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copy number analysis

By identifying inherited, rare copy number variants specific to families affected by autism spectrum disorders, researchers have identified several biological pathways that may contribute to the disease.

Four genome sequencing and comparison studies are offering insights into the various strategies that plant pathogens have devised for infecting their hosts.

By genotyping more than 1,000 individuals with anorexia nervosa and almost 4,000 unaffected controls, researchers have identified common SNPs and rare CNVs that appear to be linked to the condition.

Using array comparative genomic hybridization, a team of researchers from the US looked at copy number patterns in dozens of healthy, pre-cancerous, and cancerous skin samples, identifying a recurrent chromosome 10 deletion associated with an aggressive form of skin cancer called cutaneous squamous cell carcinoma.

Researchers from Norway, Belgium, and elsewhere have developed an algorithm for determining allele-specific copy number patterns in tumors from SNP data.

Macrogen will offer services in Korea using CGH/CNV tools from Roche NimbleGen.

The research team analyzed a combination of DNA sequence, copy number, and mRNA expression to identify several genes associated with soft-tissue sarcoma subtypes.

The agreement covers Agilent's Mx3005P qPCR system and Brilliant qPCR reagents and IDT's PrimeTime qPCR assays.

The technique could be used to diagnose diseases such as mental retardation, where copy number variation is a key characteristic, and as a screening tool to look for cancer biomarkers and assess drug effectiveness, the researchers said.

An international consortium has identified rare copy number variants that are more common in individuals on the autism spectrum.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.