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copy number analysis

A method called G&T-seq physically separates single-cell DNA from messenger RNA for subsequent sequencing.

Researchers did genome sequencing and copy number testing on samples from 100 pancreatic ductal carcinoma patients, building on prior ICGC exome findings.

Researchers looked at the relationship between survival and tumor diversity in more than a dozen individuals with high-grade serous ovarian cancer. 

Using an algorithm known as HotNet2, an international team has identified more than a dozen genetically altered sub-networks in thousands of tumor samples assessed for the Cancer Genome Atlas project.

NEW YORK (GenomeWeb) — An analysis of data from The Cancer Genome Atlas' comprehensive molecular profiling of squamous cell head and neck cancer has revealed a more complicated molecular landscape for the disease, and has identified a new genomic subset that indicates particularly poor survival.

NEW YORK (GenomeWeb News) – Two forms of a rare subgroup of acute lymphoblastic leukemia form through chromothripsis, or catastrophic chromosome shattering, researchers from the Wellcome Trust S

NEW YORK (GenomeWeb News) – Genes involved in chromatin regulation are amongst those most prone to recurrent mutation in urothelial bladder cancer, according to a new Nature study from members of the Cancer Genome Atlas.

NEW YORK (GenomeWeb News) – Similar to human breast cancers, canine mammary tumors are beset by chromosome instability, researchers from Chronix Biomedical and the Institute of Veterinary Medicine at the University of Göttingen in Germany reported in PLOS One yesterday.

NEW YORK (GenomeWeb News) – A flurry of new studies is outlining findings from the first phase of an analysis that brings together Cancer Genome Atlas data on up to a dozen cancer types.

NEW YORK (GenomeWeb News) – A Japanese team has published an integrated genomic and transcriptomic analysis focused on a form of kidney cancer called clear-cell renal cell carcinoma.

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New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.